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Doxorubicin and Aclarubicin: Shuffling Anthracycline Glycans for Improved Anticancer Agents

[Image: see text] Anthracycline anticancer drugs doxorubicin and aclarubicin have been used in the clinic for several decades to treat various cancers. Although closely related structures, their molecular mode of action diverges, which is reflected in their biological activity profile. For a better...

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Detalles Bibliográficos
Autores principales:	Wander, Dennis P. A., van der Zanden, Sabina Y., van der Marel, Gijsbert A., Overkleeft, Herman S., Neefjes, Jacques, Codée, Jeroen D. C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2020
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667640/ https://www.ncbi.nlm.nih.gov/pubmed/33064004 http://dx.doi.org/10.1021/acs.jmedchem.0c01191

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