Silencing of miR-138-5p sensitizes bone anabolic action to mechanical stimuli

Emerging evidence is revealing that microRNAs (miRNAs) play essential roles in mechanosensing for regulating osteogenesis. However, no mechanoresponsive miRNAs have been identified in human bone specimens. Methods: Bedridden and aged patients, hindlimb unloaded and aged mice, and Random Positioning...

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Detalles Bibliográficos
Autores principales: Chen, Zhihao, Zhao, Fan, Liang, Chao, Hu, Lifang, Li, Dijie, Zhang, Yan, Yin, Chong, Chen, Lei, Wang, Luyao, Lin, Xiao, Su, Peihong, Ma, Jianhua, Yang, Chaofei, Tian, Ye, Zhang, Wenjuan, Li, Yu, Peng, Songlin, Chen, Weiyi, Zhang, Ge, Qian, Airong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667683/
https://www.ncbi.nlm.nih.gov/pubmed/33204341
http://dx.doi.org/10.7150/thno.53009

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