ITGB2-mediated metabolic switch in CAFs promotes OSCC proliferation by oxidation of NADH in mitochondrial oxidative phosphorylation system

Objectives: Integrins, the coordinator of extracellular and intracellular signaling, are often found to be aberrant in tumors and can reshape the tumor microenvironment. Although previous studies showed that integrin beta 2 (ITGB2) is important for host defense, its expression profile and role in tu...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoxin, Dong, Yingchun, Zhao, Mengxiang, Ding, Liang, Yang, Xihu, Jing, Yue, Song, Yuxian, Chen, Sheng, Hu, Qingang, Ni, Yanhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667693/
https://www.ncbi.nlm.nih.gov/pubmed/33204328
http://dx.doi.org/10.7150/thno.47901

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