Cargando…
Stability and bifurcations in a discrete-time epidemic model with vaccination and vital dynamics
BACKGROUND: The spread of infectious diseases is so important that changes the demography of the population. Therefore, prevention and intervention measures are essential to control and eliminate the disease. Among the drug and non-drug interventions, vaccination is a powerful strategy to preserve t...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667759/ https://www.ncbi.nlm.nih.gov/pubmed/33198622 http://dx.doi.org/10.1186/s12859-020-03839-1 |
_version_ | 1783610376787591168 |
---|---|
author | Parsamanesh, Mahmood Erfanian, Majid Mehrshad, Saeed |
author_facet | Parsamanesh, Mahmood Erfanian, Majid Mehrshad, Saeed |
author_sort | Parsamanesh, Mahmood |
collection | PubMed |
description | BACKGROUND: The spread of infectious diseases is so important that changes the demography of the population. Therefore, prevention and intervention measures are essential to control and eliminate the disease. Among the drug and non-drug interventions, vaccination is a powerful strategy to preserve the population from infection. Mathematical models are useful to study the behavior of an infection when it enters a population and to investigate under which conditions it will be wiped out or continued. RESULTS: A discrete-time SIS epidemic model is introduced that includes a vaccination program. Some basic properties of this model are obtained; such as the equilibria and the basic reproduction number [Formula: see text] . Then the stability of the equilibria is given in terms of [Formula: see text] , and the bifurcations of the model are studied. By applying the forward Euler method on the continuous version of the model, a discretized model is obtained and analyzed. CONCLUSION: It is proven that the disease-free equilibrium and endemic equilibrium are stable if [Formula: see text] and [Formula: see text] , respectively. Also, the disease-free equilibrium is globally stable when [Formula: see text] . The system has a transcritical bifurcation when [Formula: see text] and it might also have period-doubling bifurcation. The sufficient conditions for the stability of equilibria in the discretized model are established. The numerical discussions verify the theoretical results. |
format | Online Article Text |
id | pubmed-7667759 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-76677592020-11-17 Stability and bifurcations in a discrete-time epidemic model with vaccination and vital dynamics Parsamanesh, Mahmood Erfanian, Majid Mehrshad, Saeed BMC Bioinformatics Research Article BACKGROUND: The spread of infectious diseases is so important that changes the demography of the population. Therefore, prevention and intervention measures are essential to control and eliminate the disease. Among the drug and non-drug interventions, vaccination is a powerful strategy to preserve the population from infection. Mathematical models are useful to study the behavior of an infection when it enters a population and to investigate under which conditions it will be wiped out or continued. RESULTS: A discrete-time SIS epidemic model is introduced that includes a vaccination program. Some basic properties of this model are obtained; such as the equilibria and the basic reproduction number [Formula: see text] . Then the stability of the equilibria is given in terms of [Formula: see text] , and the bifurcations of the model are studied. By applying the forward Euler method on the continuous version of the model, a discretized model is obtained and analyzed. CONCLUSION: It is proven that the disease-free equilibrium and endemic equilibrium are stable if [Formula: see text] and [Formula: see text] , respectively. Also, the disease-free equilibrium is globally stable when [Formula: see text] . The system has a transcritical bifurcation when [Formula: see text] and it might also have period-doubling bifurcation. The sufficient conditions for the stability of equilibria in the discretized model are established. The numerical discussions verify the theoretical results. BioMed Central 2020-11-16 /pmc/articles/PMC7667759/ /pubmed/33198622 http://dx.doi.org/10.1186/s12859-020-03839-1 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Article Parsamanesh, Mahmood Erfanian, Majid Mehrshad, Saeed Stability and bifurcations in a discrete-time epidemic model with vaccination and vital dynamics |
title | Stability and bifurcations in a discrete-time epidemic model with vaccination and vital dynamics |
title_full | Stability and bifurcations in a discrete-time epidemic model with vaccination and vital dynamics |
title_fullStr | Stability and bifurcations in a discrete-time epidemic model with vaccination and vital dynamics |
title_full_unstemmed | Stability and bifurcations in a discrete-time epidemic model with vaccination and vital dynamics |
title_short | Stability and bifurcations in a discrete-time epidemic model with vaccination and vital dynamics |
title_sort | stability and bifurcations in a discrete-time epidemic model with vaccination and vital dynamics |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667759/ https://www.ncbi.nlm.nih.gov/pubmed/33198622 http://dx.doi.org/10.1186/s12859-020-03839-1 |
work_keys_str_mv | AT parsamaneshmahmood stabilityandbifurcationsinadiscretetimeepidemicmodelwithvaccinationandvitaldynamics AT erfanianmajid stabilityandbifurcationsinadiscretetimeepidemicmodelwithvaccinationandvitaldynamics AT mehrshadsaeed stabilityandbifurcationsinadiscretetimeepidemicmodelwithvaccinationandvitaldynamics |