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Prevalence and risk factors of chronic kidney disease among Palestinian type 2 diabetic patients: a cross-sectional study
BACKGROUND: Chronic kidney disease (CKD) is a global public health concern and diabetes is one of the main risk factors for its occurrence and progression. The aim of this research is to determine the prevalence of chronic kidney disease in a cross-sectional population of patients with type 2 diabet...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667814/ https://www.ncbi.nlm.nih.gov/pubmed/33198669 http://dx.doi.org/10.1186/s12882-020-02138-4 |
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author | Nazzal, Zaher Hamdan, Zakaria Masri, Dunia Abu-Kaf, Oday Hamad, Mohammad |
author_facet | Nazzal, Zaher Hamdan, Zakaria Masri, Dunia Abu-Kaf, Oday Hamad, Mohammad |
author_sort | Nazzal, Zaher |
collection | PubMed |
description | BACKGROUND: Chronic kidney disease (CKD) is a global public health concern and diabetes is one of the main risk factors for its occurrence and progression. The aim of this research is to determine the prevalence of chronic kidney disease in a cross-sectional population of patients with type 2 diabetes in primary health centers in North West Bank. METHODS: Patient data including patient characteristics, creatinine level, blood pressure, HbA1c, and hypertension and period of diabetes were obtained from primary health care centers. The eGFR has been determined using the CKD-EPI equation. CKD was staged according to the 2012 Kidney Disease Improving Global Outcomes Framework (KDIGO) guideline. Both univariable and multivariable statistical analysis was conducted using SPSS. RESULTS: The prevalence of chronic kidney disease among diabetic adults in North West Bank was found to be 23.6% (95% CI: 19.4–28.1%) divided as follows: 19.7% had stage 3 CKD, 2.6% had stage 4 CKD and 1.3% had stage 5 CKD. In multivariable logistic regression, CKD was significantly associated with Age ≥ 60 years [adjusted OR: 3.2, 95% CI: 1.8–5.9], hypertension [adjusted OR: 5.7, 95% CI: 2.2–15.2], and smoking [adjusted OR: 2.3, 95% CI: 1.3–4.2]. CONCLUSIONS: CKD is very prevalent among diabetic adults in Palestine. Co-morbid hypertension, smoking and older age has been shown to increase the risk of developing CKD. Extensive screening for diabetic patients to diagnose CKD at an early stage and to follow more aggressive treatment methods for diabetes as well as other important risk factors, especially hypertension and smoking, is recommended. |
format | Online Article Text |
id | pubmed-7667814 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-76678142020-11-17 Prevalence and risk factors of chronic kidney disease among Palestinian type 2 diabetic patients: a cross-sectional study Nazzal, Zaher Hamdan, Zakaria Masri, Dunia Abu-Kaf, Oday Hamad, Mohammad BMC Nephrol Research Article BACKGROUND: Chronic kidney disease (CKD) is a global public health concern and diabetes is one of the main risk factors for its occurrence and progression. The aim of this research is to determine the prevalence of chronic kidney disease in a cross-sectional population of patients with type 2 diabetes in primary health centers in North West Bank. METHODS: Patient data including patient characteristics, creatinine level, blood pressure, HbA1c, and hypertension and period of diabetes were obtained from primary health care centers. The eGFR has been determined using the CKD-EPI equation. CKD was staged according to the 2012 Kidney Disease Improving Global Outcomes Framework (KDIGO) guideline. Both univariable and multivariable statistical analysis was conducted using SPSS. RESULTS: The prevalence of chronic kidney disease among diabetic adults in North West Bank was found to be 23.6% (95% CI: 19.4–28.1%) divided as follows: 19.7% had stage 3 CKD, 2.6% had stage 4 CKD and 1.3% had stage 5 CKD. In multivariable logistic regression, CKD was significantly associated with Age ≥ 60 years [adjusted OR: 3.2, 95% CI: 1.8–5.9], hypertension [adjusted OR: 5.7, 95% CI: 2.2–15.2], and smoking [adjusted OR: 2.3, 95% CI: 1.3–4.2]. CONCLUSIONS: CKD is very prevalent among diabetic adults in Palestine. Co-morbid hypertension, smoking and older age has been shown to increase the risk of developing CKD. Extensive screening for diabetic patients to diagnose CKD at an early stage and to follow more aggressive treatment methods for diabetes as well as other important risk factors, especially hypertension and smoking, is recommended. BioMed Central 2020-11-16 /pmc/articles/PMC7667814/ /pubmed/33198669 http://dx.doi.org/10.1186/s12882-020-02138-4 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Article Nazzal, Zaher Hamdan, Zakaria Masri, Dunia Abu-Kaf, Oday Hamad, Mohammad Prevalence and risk factors of chronic kidney disease among Palestinian type 2 diabetic patients: a cross-sectional study |
title | Prevalence and risk factors of chronic kidney disease among Palestinian type 2 diabetic patients: a cross-sectional study |
title_full | Prevalence and risk factors of chronic kidney disease among Palestinian type 2 diabetic patients: a cross-sectional study |
title_fullStr | Prevalence and risk factors of chronic kidney disease among Palestinian type 2 diabetic patients: a cross-sectional study |
title_full_unstemmed | Prevalence and risk factors of chronic kidney disease among Palestinian type 2 diabetic patients: a cross-sectional study |
title_short | Prevalence and risk factors of chronic kidney disease among Palestinian type 2 diabetic patients: a cross-sectional study |
title_sort | prevalence and risk factors of chronic kidney disease among palestinian type 2 diabetic patients: a cross-sectional study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667814/ https://www.ncbi.nlm.nih.gov/pubmed/33198669 http://dx.doi.org/10.1186/s12882-020-02138-4 |
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