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The tail of cryptochromes: an intrinsically disordered cog within the mammalian circadian clock

Cryptochrome (CRY) proteins play an essential role in regulating mammalian circadian rhythms. CRY is composed of a structured N-terminal domain known as the photolyase homology region (PHR), which is tethered to an intrinsically disordered C-terminal tail. The PHR domain is a critical hub for bindin...

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Detalles Bibliográficos
Autores principales:	Parico, Gian Carlo G., Partch, Carrie L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Commentary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667820/ https://www.ncbi.nlm.nih.gov/pubmed/33198762 http://dx.doi.org/10.1186/s12964-020-00665-z

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