IL‐2/IL‐7‐inducible factors pioneer the path to T cell differentiation in advance of lineage‐defining factors

When dormant naïve T cells first become activated by antigen‐presenting cells, they express the autocrine growth factor IL‐2 which transforms them into rapidly dividing effector T cells. During this process, hundreds of genes undergo epigenetic reprogramming for efficient activation, and also for po...

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Detalles Bibliográficos
Autores principales: Bevington, Sarah L, Keane, Peter, Soley, Jake K, Tauch, Saskia, Gajdasik, Dominika W, Fiancette, Remi, Matei‐Rascu, Veronika, Willis, Claire M, Withers, David R, Cockerill, Peter N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667885/
https://www.ncbi.nlm.nih.gov/pubmed/32930455
http://dx.doi.org/10.15252/embj.2020105220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667885/
https://www.ncbi.nlm.nih.gov/pubmed/32930455
http://dx.doi.org/10.15252/embj.2020105220

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