Cargando…

Predictive accuracy of a hierarchical logistic model of cumulative SARS-CoV-2 case growth until May 2020

BACKGROUND: Infectious disease predictions models, including virtually all epidemiological models describing the spread of the SARS-CoV-2 pandemic, are rarely evaluated empirically. The aim of the present study was to investigate the predictive accuracy of a prognostic model for forecasting the deve...

Descripción completa

Detalles Bibliográficos
Autor principal: Kriston, Levente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668026/
https://www.ncbi.nlm.nih.gov/pubmed/33198633
http://dx.doi.org/10.1186/s12874-020-01160-2
_version_ 1783610419087147008
author Kriston, Levente
author_facet Kriston, Levente
author_sort Kriston, Levente
collection PubMed
description BACKGROUND: Infectious disease predictions models, including virtually all epidemiological models describing the spread of the SARS-CoV-2 pandemic, are rarely evaluated empirically. The aim of the present study was to investigate the predictive accuracy of a prognostic model for forecasting the development of the cumulative number of reported SARS-CoV-2 cases in countries and administrative regions worldwide until the end of May 2020. METHODS: The cumulative number of reported SARS-CoV-2 cases was forecasted in 251 regions with a horizon of two weeks, one month, and two months using a hierarchical logistic model at the end of March 2020. Forecasts were compared to actual observations by using a series of evaluation metrics. RESULTS: On average, predictive accuracy was very high in nearly all regions at the two weeks forecast, high in most regions at the one month forecast, and notable in the majority of the regions at the two months forecast. Higher accuracy was associated with the availability of more data for estimation and with a more pronounced cumulative case growth from the first case to the date of estimation. In some strongly affected regions, cumulative case counts were considerably underestimated. CONCLUSIONS: With keeping its limitations in mind, the investigated model may be used for the preparation and distribution of resources during the initial phase of epidemics. Future research should primarily address the model’s assumptions and its scope of applicability. In addition, establishing a relationship with known mechanisms and traditional epidemiological models of disease transmission would be desirable.
format Online
Article
Text
id pubmed-7668026
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-76680262020-11-16 Predictive accuracy of a hierarchical logistic model of cumulative SARS-CoV-2 case growth until May 2020 Kriston, Levente BMC Med Res Methodol Research Article BACKGROUND: Infectious disease predictions models, including virtually all epidemiological models describing the spread of the SARS-CoV-2 pandemic, are rarely evaluated empirically. The aim of the present study was to investigate the predictive accuracy of a prognostic model for forecasting the development of the cumulative number of reported SARS-CoV-2 cases in countries and administrative regions worldwide until the end of May 2020. METHODS: The cumulative number of reported SARS-CoV-2 cases was forecasted in 251 regions with a horizon of two weeks, one month, and two months using a hierarchical logistic model at the end of March 2020. Forecasts were compared to actual observations by using a series of evaluation metrics. RESULTS: On average, predictive accuracy was very high in nearly all regions at the two weeks forecast, high in most regions at the one month forecast, and notable in the majority of the regions at the two months forecast. Higher accuracy was associated with the availability of more data for estimation and with a more pronounced cumulative case growth from the first case to the date of estimation. In some strongly affected regions, cumulative case counts were considerably underestimated. CONCLUSIONS: With keeping its limitations in mind, the investigated model may be used for the preparation and distribution of resources during the initial phase of epidemics. Future research should primarily address the model’s assumptions and its scope of applicability. In addition, establishing a relationship with known mechanisms and traditional epidemiological models of disease transmission would be desirable. BioMed Central 2020-11-16 /pmc/articles/PMC7668026/ /pubmed/33198633 http://dx.doi.org/10.1186/s12874-020-01160-2 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Kriston, Levente
Predictive accuracy of a hierarchical logistic model of cumulative SARS-CoV-2 case growth until May 2020
title Predictive accuracy of a hierarchical logistic model of cumulative SARS-CoV-2 case growth until May 2020
title_full Predictive accuracy of a hierarchical logistic model of cumulative SARS-CoV-2 case growth until May 2020
title_fullStr Predictive accuracy of a hierarchical logistic model of cumulative SARS-CoV-2 case growth until May 2020
title_full_unstemmed Predictive accuracy of a hierarchical logistic model of cumulative SARS-CoV-2 case growth until May 2020
title_short Predictive accuracy of a hierarchical logistic model of cumulative SARS-CoV-2 case growth until May 2020
title_sort predictive accuracy of a hierarchical logistic model of cumulative sars-cov-2 case growth until may 2020
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668026/
https://www.ncbi.nlm.nih.gov/pubmed/33198633
http://dx.doi.org/10.1186/s12874-020-01160-2
work_keys_str_mv AT kristonlevente predictiveaccuracyofahierarchicallogisticmodelofcumulativesarscov2casegrowthuntilmay2020