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Amyloid formation of fish β-parvalbumin involves primary nucleation triggered by disulfide-bridged protein dimers
Amyloid formation involves the conversion of soluble protein species to an aggregated state. Amyloid fibrils of β-parvalbumin, a protein abundant in fish, act as an allergen but also inhibit the in vitro assembly of the Parkinson protein α-synuclein. However, the intrinsic aggregation mechanism of β...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668186/ https://www.ncbi.nlm.nih.gov/pubmed/33093204 http://dx.doi.org/10.1073/pnas.2015503117 |