Identification of L-asparaginases from Streptomyces strains with competitive activity and immunogenic profiles: a bioinformatic approach

The enzyme L-asparaginase from Escherichia coli is a therapeutic enzyme that has been a cornerstone in the clinical treatment of acute lymphoblastic leukemia for the last decades. However, treatment effectiveness is limited by the highly immunogenic nature of the protein and its cross-reactivity tow...

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Detalles Bibliográficos
Autores principales: González-Torres, Iván, Perez-Rueda, Ernesto, Evangelista-Martínez, Zahaed, Zárate-Romero, Andrés, Moreno-Enríquez, Angélica, Huerta-Saquero, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668207/
https://www.ncbi.nlm.nih.gov/pubmed/33240625
http://dx.doi.org/10.7717/peerj.10276

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668207/
https://www.ncbi.nlm.nih.gov/pubmed/33240625
http://dx.doi.org/10.7717/peerj.10276

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