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Synthesis of potentially new schiff bases of N-substituted-2-quinolonylacetohydrazides as anti-COVID-19 agents

We report herein a new series of synthesized N-substituted-2-quinolonylacetohydrazides aiming to evaluate their activity towards SARS-CoV-2. The structures of the obtained products were fully confirmed by NMR, mass, IR spectra and elemental analysis as well. Molecular docking calculations showed tha...

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Detalles Bibliográficos
Autores principales: Alshammari, Mohammed B., Ramadan, Mohamed, Aly, Ashraf A., El-Sheref, Essmat M., Bakht, Md Afroz, Ibrahim, Mahmoud A.A., Shawky, Ahmed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668221/
https://www.ncbi.nlm.nih.gov/pubmed/33223566
http://dx.doi.org/10.1016/j.molstruc.2020.129649