Cargando…

Chemical shifts-based similarity restraints improve accuracy of RNA structures determined via NMR

Determination of structure of RNA via NMR is complicated in large part by the lack of a precise parameterization linking the observed chemical shifts to the underlying geometric parameters. In contrast to proteins, where numerous high-resolution crystal structures serve as coordinate templates for t...

Descripción completa

Detalles Bibliográficos
Autores principales: Lawrence, Chad, Grishaev, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668244/
https://www.ncbi.nlm.nih.gov/pubmed/32917774
http://dx.doi.org/10.1261/rna.074617.119