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Chemical shifts-based similarity restraints improve accuracy of RNA structures determined via NMR
Determination of structure of RNA via NMR is complicated in large part by the lack of a precise parameterization linking the observed chemical shifts to the underlying geometric parameters. In contrast to proteins, where numerous high-resolution crystal structures serve as coordinate templates for t...
Autores principales: | Lawrence, Chad, Grishaev, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668244/ https://www.ncbi.nlm.nih.gov/pubmed/32917774 http://dx.doi.org/10.1261/rna.074617.119 |
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