Cargando…
Processing of Alu small RNAs by DICER/ADAR1 complexes and their RNAi targets
In addition to adenosine-to-inosine RNA editing activities, ADAR1 has been shown to have various RNA editing-independent activities including modulation of RNAi efficacy. We previously reported that ADAR1 forms a heterodimer complex with DICER and facilitates processing of pre-miRNAs to mature miRNA...
Autores principales: | Shiromoto, Yusuke, Sakurai, Masayuki, Qu, Helen, Kossenkov, Andrew V., Nishikura, Kazuko |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668262/ https://www.ncbi.nlm.nih.gov/pubmed/32817447 http://dx.doi.org/10.1261/rna.076745.120 |
Ejemplares similares
-
Functions of the RNA Editing Enzyme ADAR1 and Their Relevance to Human Diseases
por: Song, Chunzi, et al.
Publicado: (2016) -
ADAR1 RNA editing enzyme regulates R-loop formation and genome stability at telomeres in cancer cells
por: Shiromoto, Yusuke, et al.
Publicado: (2021) -
ADAR1 controls apoptosis of stressed cells by inhibiting Staufen1-mediated mRNA decay
por: Sakurai, Masayuki, et al.
Publicado: (2017) -
A rADAR defense against RNAi
por: Pasquinelli, Amy E.
Publicado: (2018) -
C. elegans ADARs antagonize silencing of cellular dsRNAs by the antiviral RNAi pathway
por: Reich, Daniel P., et al.
Publicado: (2018)