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The Effect of Perioperative Music on Medication Requirement and Hospital Length of Stay: A Meta-analysis

OBJECTIVE: To assess and quantify the effect of perioperative music on medication requirement, length of stay and costs in adult surgical patients. SUMMARY BACKGROUND DATA: There is an increasing interest in nonpharmacological interventions to decrease opioid analgesics use, as they have significant...

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Autores principales: Fu, Victor X., Oomens, Pim, Klimek, Markus, Verhofstad, Michiel H. J., Jeekel, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668322/
https://www.ncbi.nlm.nih.gov/pubmed/31356272
http://dx.doi.org/10.1097/SLA.0000000000003506
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author Fu, Victor X.
Oomens, Pim
Klimek, Markus
Verhofstad, Michiel H. J.
Jeekel, Johannes
author_facet Fu, Victor X.
Oomens, Pim
Klimek, Markus
Verhofstad, Michiel H. J.
Jeekel, Johannes
author_sort Fu, Victor X.
collection PubMed
description OBJECTIVE: To assess and quantify the effect of perioperative music on medication requirement, length of stay and costs in adult surgical patients. SUMMARY BACKGROUND DATA: There is an increasing interest in nonpharmacological interventions to decrease opioid analgesics use, as they have significant adverse effects and opioid prescription rates have reached epidemic proportions. Previous studies have reported beneficial outcomes of perioperative music. METHODS: A systematic literature search of 8 databases was performed from inception date to January 7, 2019. Randomized controlled trials investigating the effect of perioperative music on medication requirement, length of stay or costs in adult surgical patients were eligible. Meta-analysis was performed using random effect models, pooled standardized mean differences (SMD) were calculated with 95% confidence intervals (CI). This study was registered with PROSPERO (CRD42018093140) and adhered to the Preferred Reporting Items for Systematic Reviews and Meta-analysis guidelines. RESULTS: The literature search yielded 2414 articles, 55 studies (N = 4968 patients) were included. Perioperative music significantly reduced postoperative opioid requirement (pooled SMD −0.31 [95% CI −0.45 to −0.16], P < 0.001, I (2) = 44.3, N = 1398). Perioperative music also significantly reduced intraoperative propofol (pooled SMD −0.72 [95% CI −1.01 to −0.43], P < 0.00001, I (2) = 61.1, N = 554) and midazolam requirement (pooled SMD −1.07 [95% CI −1.70 to −0.44], P < 0.001, I (2) = 73.1, N = 184), while achieving the same sedation level. No significant reduction in length of stay (pooled SMD −0.18 [95% CI −0.43 to 0.067], P = 0.15, I (2) = 56.0, N = 600) was observed. CONCLUSIONS: Perioperative music can reduce opioid and sedative medication requirement, potentially improving patient outcome and reducing medical costs as higher opioid dosage is associated with an increased risk of adverse events and chronic opioid abuse.
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spelling pubmed-76683222020-11-16 The Effect of Perioperative Music on Medication Requirement and Hospital Length of Stay: A Meta-analysis Fu, Victor X. Oomens, Pim Klimek, Markus Verhofstad, Michiel H. J. Jeekel, Johannes Ann Surg Meta-Analysis OBJECTIVE: To assess and quantify the effect of perioperative music on medication requirement, length of stay and costs in adult surgical patients. SUMMARY BACKGROUND DATA: There is an increasing interest in nonpharmacological interventions to decrease opioid analgesics use, as they have significant adverse effects and opioid prescription rates have reached epidemic proportions. Previous studies have reported beneficial outcomes of perioperative music. METHODS: A systematic literature search of 8 databases was performed from inception date to January 7, 2019. Randomized controlled trials investigating the effect of perioperative music on medication requirement, length of stay or costs in adult surgical patients were eligible. Meta-analysis was performed using random effect models, pooled standardized mean differences (SMD) were calculated with 95% confidence intervals (CI). This study was registered with PROSPERO (CRD42018093140) and adhered to the Preferred Reporting Items for Systematic Reviews and Meta-analysis guidelines. RESULTS: The literature search yielded 2414 articles, 55 studies (N = 4968 patients) were included. Perioperative music significantly reduced postoperative opioid requirement (pooled SMD −0.31 [95% CI −0.45 to −0.16], P < 0.001, I (2) = 44.3, N = 1398). Perioperative music also significantly reduced intraoperative propofol (pooled SMD −0.72 [95% CI −1.01 to −0.43], P < 0.00001, I (2) = 61.1, N = 554) and midazolam requirement (pooled SMD −1.07 [95% CI −1.70 to −0.44], P < 0.001, I (2) = 73.1, N = 184), while achieving the same sedation level. No significant reduction in length of stay (pooled SMD −0.18 [95% CI −0.43 to 0.067], P = 0.15, I (2) = 56.0, N = 600) was observed. CONCLUSIONS: Perioperative music can reduce opioid and sedative medication requirement, potentially improving patient outcome and reducing medical costs as higher opioid dosage is associated with an increased risk of adverse events and chronic opioid abuse. Lippincott Williams & Wilkins 2020-12 2019-07-26 /pmc/articles/PMC7668322/ /pubmed/31356272 http://dx.doi.org/10.1097/SLA.0000000000003506 Text en Copyright © 2020 The Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0
spellingShingle Meta-Analysis
Fu, Victor X.
Oomens, Pim
Klimek, Markus
Verhofstad, Michiel H. J.
Jeekel, Johannes
The Effect of Perioperative Music on Medication Requirement and Hospital Length of Stay: A Meta-analysis
title The Effect of Perioperative Music on Medication Requirement and Hospital Length of Stay: A Meta-analysis
title_full The Effect of Perioperative Music on Medication Requirement and Hospital Length of Stay: A Meta-analysis
title_fullStr The Effect of Perioperative Music on Medication Requirement and Hospital Length of Stay: A Meta-analysis
title_full_unstemmed The Effect of Perioperative Music on Medication Requirement and Hospital Length of Stay: A Meta-analysis
title_short The Effect of Perioperative Music on Medication Requirement and Hospital Length of Stay: A Meta-analysis
title_sort effect of perioperative music on medication requirement and hospital length of stay: a meta-analysis
topic Meta-Analysis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668322/
https://www.ncbi.nlm.nih.gov/pubmed/31356272
http://dx.doi.org/10.1097/SLA.0000000000003506
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