Vaccine-induced CD8 T cells are redirected with peptide-MHC class I-IgG antibody fusion proteins to eliminate tumor cells in vivo

Simulating a viral infection in tumor cells is an attractive concept to eliminate tumor cells. We previously reported the molecular design and the in vitro potency of recombinant monoclonal antibodies fused to a virus-derived peptide MHC class I complex that bypass the peptide processing and MHC loa...

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Detalles Bibliográficos
Autores principales: Fischer, Cornelia, Munks, Michael W., Hill, Ann B., Kroczek, Richard A., Bissinger, Stefan, Brand, Verena, Schmittnaegel, Martina, Imhof-Jung, Sabine, Hoffmann, Eike, Herting, Frank, Klein, Christian, Knoetgen, Hendrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668529/
https://www.ncbi.nlm.nih.gov/pubmed/33151105
http://dx.doi.org/10.1080/19420862.2020.1834818

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