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A simple method to estimate flow restriction for dual ventilation of dissimilar patients: The BathRC model
BACKGROUND: With large numbers of COVID-19 patients requiring mechanical ventilation and ventilators possibly being in short supply, in extremis two patients may have to share one ventilator. Careful matching of patient ventilation requirements is necessary. However, good matching is difficult to ac...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668571/ https://www.ncbi.nlm.nih.gov/pubmed/33196687 http://dx.doi.org/10.1371/journal.pone.0242123 |
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author | Plummer, Andrew R. du Bois, Jonathan L. Flynn, Joseph M. Roesner, Jens Lee, Siu Man Magee, Patrick Thornton, Malcolm Padkin, Andrew Gill, Harinderjit S. |
author_facet | Plummer, Andrew R. du Bois, Jonathan L. Flynn, Joseph M. Roesner, Jens Lee, Siu Man Magee, Patrick Thornton, Malcolm Padkin, Andrew Gill, Harinderjit S. |
author_sort | Plummer, Andrew R. |
collection | PubMed |
description | BACKGROUND: With large numbers of COVID-19 patients requiring mechanical ventilation and ventilators possibly being in short supply, in extremis two patients may have to share one ventilator. Careful matching of patient ventilation requirements is necessary. However, good matching is difficult to achieve as lung characteristics can have a wide range and may vary over time. Adding flow restriction to the flow path between ventilator and patient gives the opportunity to control the airway pressure and hence flow and volume individually for each patient. This study aimed to create and validate a simple model for calculating required flow restriction. METHODS AND FINDINGS: We created a simple linear resistance-compliance model, termed the BathRC model, of the ventilator tubing system and lung allowing direct calculation of the relationships between pressures, volumes, and required flow restriction. Experimental measurements were made for parameter determination and validation using a clinical ventilator connected to two test lungs. For validation, differing amounts of restriction were introduced into the ventilator circuit. The BathRC model was able to predict tidal lung volumes with a mean error of 4% (min:1.2%, max:9.3%). CONCLUSION: We present a simple model validated model that can be used to estimate required flow restriction for dual patient ventilation. The BathRC model is freely available; this tool is provided to demonstrate that flow restriction can be readily estimated. Models and data are available at DOI 10.15125/BATH-00816. |
format | Online Article Text |
id | pubmed-7668571 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-76685712020-11-19 A simple method to estimate flow restriction for dual ventilation of dissimilar patients: The BathRC model Plummer, Andrew R. du Bois, Jonathan L. Flynn, Joseph M. Roesner, Jens Lee, Siu Man Magee, Patrick Thornton, Malcolm Padkin, Andrew Gill, Harinderjit S. PLoS One Research Article BACKGROUND: With large numbers of COVID-19 patients requiring mechanical ventilation and ventilators possibly being in short supply, in extremis two patients may have to share one ventilator. Careful matching of patient ventilation requirements is necessary. However, good matching is difficult to achieve as lung characteristics can have a wide range and may vary over time. Adding flow restriction to the flow path between ventilator and patient gives the opportunity to control the airway pressure and hence flow and volume individually for each patient. This study aimed to create and validate a simple model for calculating required flow restriction. METHODS AND FINDINGS: We created a simple linear resistance-compliance model, termed the BathRC model, of the ventilator tubing system and lung allowing direct calculation of the relationships between pressures, volumes, and required flow restriction. Experimental measurements were made for parameter determination and validation using a clinical ventilator connected to two test lungs. For validation, differing amounts of restriction were introduced into the ventilator circuit. The BathRC model was able to predict tidal lung volumes with a mean error of 4% (min:1.2%, max:9.3%). CONCLUSION: We present a simple model validated model that can be used to estimate required flow restriction for dual patient ventilation. The BathRC model is freely available; this tool is provided to demonstrate that flow restriction can be readily estimated. Models and data are available at DOI 10.15125/BATH-00816. Public Library of Science 2020-11-16 /pmc/articles/PMC7668571/ /pubmed/33196687 http://dx.doi.org/10.1371/journal.pone.0242123 Text en © 2020 Plummer et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Plummer, Andrew R. du Bois, Jonathan L. Flynn, Joseph M. Roesner, Jens Lee, Siu Man Magee, Patrick Thornton, Malcolm Padkin, Andrew Gill, Harinderjit S. A simple method to estimate flow restriction for dual ventilation of dissimilar patients: The BathRC model |
title | A simple method to estimate flow restriction for dual ventilation of dissimilar patients: The BathRC model |
title_full | A simple method to estimate flow restriction for dual ventilation of dissimilar patients: The BathRC model |
title_fullStr | A simple method to estimate flow restriction for dual ventilation of dissimilar patients: The BathRC model |
title_full_unstemmed | A simple method to estimate flow restriction for dual ventilation of dissimilar patients: The BathRC model |
title_short | A simple method to estimate flow restriction for dual ventilation of dissimilar patients: The BathRC model |
title_sort | simple method to estimate flow restriction for dual ventilation of dissimilar patients: the bathrc model |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668571/ https://www.ncbi.nlm.nih.gov/pubmed/33196687 http://dx.doi.org/10.1371/journal.pone.0242123 |
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