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Divergent organ-specific isogenic metastatic cell lines identified using multi-omics exhibit differential drug sensitivity

BACKGROUND: Monitoring and treating metastatic progression remains a formidable task due, in part, to an inability to monitor specific differential molecular adaptations that allow the cancer to thrive within different tissue types. Hence, to develop optimal treatment strategies for metastatic disea...

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Detalles Bibliográficos
Autores principales: Winnard, Paul T., Vesuna, Farhad, Muthukumar, Sankar, Raman, Venu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668614/
https://www.ncbi.nlm.nih.gov/pubmed/33196681
http://dx.doi.org/10.1371/journal.pone.0242384