Identification of a unique TCR repertoire, consistent with a superantigen selection process in Children with Multi-system Inflammatory Syndrome

Multisystem Inflammatory Syndrome in Children (MIS-C), a hyperinflammatory syndrome associated with SARS-CoV-2 infection, shares many clinical features with toxic shock syndrome, which is triggered by bacterial superantigens. The superantigen specificity for binding different Vβ-chains results in Vβ...

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Detalles Bibliográficos
Autores principales: Porritt, Rebecca A, Paschold, Lisa, Noval Rivas, Magali, Hongying Cheng, Mary, Yonker, Lael M, Chandnani, Harsha, Lopez, Merrick, Simnica, Donjete, Schultheiß, Christoph, Santiskulvong, Chintda, Van Eyk, Jennifer, Fasano, Alessio, Bahar, Ivet, Binder, Mascha, Arditi, Moshe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668738/
https://www.ncbi.nlm.nih.gov/pubmed/33200133
http://dx.doi.org/10.1101/2020.11.09.372169

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