Cytotoxic T cells swarm by homotypic chemokine signalling

Cytotoxic T lymphocytes (CTLs) are thought to arrive at target sites either via random search or following signals by other leukocytes. Here, we reveal independent emergent behaviour in CTL populations attacking tumour masses. Primary murine CTLs coordinate their migration in a process reminiscent o...

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Detalles Bibliográficos
Autores principales: Galeano Niño, Jorge Luis, Pageon, Sophie V, Tay, Szun S, Colakoglu, Feyza, Kempe, Daryan, Hywood, Jack, Mazalo, Jessica K, Cremasco, James, Govendir, Matt A, Dagley, Laura F, Hsu, Kenneth, Rizzetto, Simone, Zieba, Jerzy, Rice, Gregory, Prior, Victoria, O'Neill, Geraldine M, Williams, Richard J, Nisbet, David R, Kramer, Belinda, Webb, Andrew I, Luciani, Fabio, Read, Mark N, Biro, Maté
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Computational and Systems Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7669268/
https://www.ncbi.nlm.nih.gov/pubmed/33046212
http://dx.doi.org/10.7554/eLife.56554

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