Cerebrospinal fluid xanthochromia after pegasparaginase hepatotoxicity in B‐cell acute lymphoblastic leukemia

Patients with B‐lineage acute lymphoblastic leukemia treated with pegasparaginase‐containing regimens can develop hepatotoxicity related to it. The systemic hyperbilirubinemia due to hepatotoxicity can lead to the development of CSF xanthochromia.

Detalles Bibliográficos
Autores principales: Moia, Riccardo, Greco, Mariangela, Boggione, Paola, Nicolosi, Maura, Bruna, Riccardo, Patriarca, Andrea, Gaidano, Gianluca, Lunghi, Monia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Clinical Images
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7669392/
https://www.ncbi.nlm.nih.gov/pubmed/33235781
http://dx.doi.org/10.1002/ccr3.3114
Descripción
Sumario:Patients with B‐lineage acute lymphoblastic leukemia treated with pegasparaginase‐containing regimens can develop hepatotoxicity related to it. The systemic hyperbilirubinemia due to hepatotoxicity can lead to the development of CSF xanthochromia.

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