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Scalable Production of Human Mesenchymal Stromal Cell-Derived Extracellular Vesicles Under Serum-/Xeno-Free Conditions in a Microcarrier-Based Bioreactor Culture System
Mesenchymal stromal cells (MSC) hold great promise for tissue engineering and cell-based therapies due to their multilineage differentiation potential and intrinsic immunomodulatory and trophic activities. Over the past years, increasing evidence has proposed extracellular vesicles (EVs) as mediator...
Autores principales: | de Almeida Fuzeta, Miguel, Bernardes, Nuno, Oliveira, Filipa D., Costa, Ana Catarina, Fernandes-Platzgummer, Ana, Farinha, José Paulo, Rodrigues, Carlos A. V., Jung, Sunghoon, Tseng, Rong-Jeng, Milligan, William, Lee, Brian, Castanho, Miguel A. R. B., Gaspar, Diana, Cabral, Joaquim M. S., da Silva, Cláudia Lobato |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7669752/ https://www.ncbi.nlm.nih.gov/pubmed/33224943 http://dx.doi.org/10.3389/fcell.2020.553444 |
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