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Uncovered self-expandable metal stents for the treatment of refractory benign colorectal anastomotic stricture
Self-expandable metal stent (SEMS) placement has been suggested as a therapeutic modality for treating benign colorectal strictures. Covered stents are generally used, given the concerns regarding the efficacy and safety of uncovered stents. Hence, few studies have evaluated the efficacy and safety...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7669833/ https://www.ncbi.nlm.nih.gov/pubmed/33199742 http://dx.doi.org/10.1038/s41598-020-76779-8 |
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author | Hong, Ji Taek Kim, Tae Jun Hong, Sung Noh Kim, Young-Ho Chang, Dong Kyung Kim, Eun Ran |
author_facet | Hong, Ji Taek Kim, Tae Jun Hong, Sung Noh Kim, Young-Ho Chang, Dong Kyung Kim, Eun Ran |
author_sort | Hong, Ji Taek |
collection | PubMed |
description | Self-expandable metal stent (SEMS) placement has been suggested as a therapeutic modality for treating benign colorectal strictures. Covered stents are generally used, given the concerns regarding the efficacy and safety of uncovered stents. Hence, few studies have evaluated the efficacy and safety of uncovered SEMSs (UCSEMSs) in patients with refractory benign colorectal anastomotic strictures. In this study, 12 patients with postoperative benign symptomatic anastomotic strictures refractory to pneumatic dilation (range, 2–9) and transient indwelling-covered SEMSs were treated using UCSEMS. All enrolled patients were men (mean age, 61 years). Stent placement was successful in all 12 patients, and early clinical success was achieved in 11 (92%) patients. Four patients (25%) showed successful clinical outcomes without further intervention, but eight patients (75%) were clinically unsuccessful, and showed stricture recurrence or functional obstructive symptoms. Three patients underwent surgery, and the remaining five patients required repeat stent procedures. Despite the high reobstruction rate, the median follow-up period after UCSEMS placement was 16.7 months, demonstrating that UCSEMS may be able to achieve medium-term symptom relief without any complications. Therefore, UCSEMS may be an alternative option in exceptional circumstances in carefully selected patients, where invasive surgical treatments, such as stoma diversion, are not an option, thereby improving patients’ quality of life. |
format | Online Article Text |
id | pubmed-7669833 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-76698332020-11-18 Uncovered self-expandable metal stents for the treatment of refractory benign colorectal anastomotic stricture Hong, Ji Taek Kim, Tae Jun Hong, Sung Noh Kim, Young-Ho Chang, Dong Kyung Kim, Eun Ran Sci Rep Article Self-expandable metal stent (SEMS) placement has been suggested as a therapeutic modality for treating benign colorectal strictures. Covered stents are generally used, given the concerns regarding the efficacy and safety of uncovered stents. Hence, few studies have evaluated the efficacy and safety of uncovered SEMSs (UCSEMSs) in patients with refractory benign colorectal anastomotic strictures. In this study, 12 patients with postoperative benign symptomatic anastomotic strictures refractory to pneumatic dilation (range, 2–9) and transient indwelling-covered SEMSs were treated using UCSEMS. All enrolled patients were men (mean age, 61 years). Stent placement was successful in all 12 patients, and early clinical success was achieved in 11 (92%) patients. Four patients (25%) showed successful clinical outcomes without further intervention, but eight patients (75%) were clinically unsuccessful, and showed stricture recurrence or functional obstructive symptoms. Three patients underwent surgery, and the remaining five patients required repeat stent procedures. Despite the high reobstruction rate, the median follow-up period after UCSEMS placement was 16.7 months, demonstrating that UCSEMS may be able to achieve medium-term symptom relief without any complications. Therefore, UCSEMS may be an alternative option in exceptional circumstances in carefully selected patients, where invasive surgical treatments, such as stoma diversion, are not an option, thereby improving patients’ quality of life. Nature Publishing Group UK 2020-11-16 /pmc/articles/PMC7669833/ /pubmed/33199742 http://dx.doi.org/10.1038/s41598-020-76779-8 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Hong, Ji Taek Kim, Tae Jun Hong, Sung Noh Kim, Young-Ho Chang, Dong Kyung Kim, Eun Ran Uncovered self-expandable metal stents for the treatment of refractory benign colorectal anastomotic stricture |
title | Uncovered self-expandable metal stents for the treatment of refractory benign colorectal anastomotic stricture |
title_full | Uncovered self-expandable metal stents for the treatment of refractory benign colorectal anastomotic stricture |
title_fullStr | Uncovered self-expandable metal stents for the treatment of refractory benign colorectal anastomotic stricture |
title_full_unstemmed | Uncovered self-expandable metal stents for the treatment of refractory benign colorectal anastomotic stricture |
title_short | Uncovered self-expandable metal stents for the treatment of refractory benign colorectal anastomotic stricture |
title_sort | uncovered self-expandable metal stents for the treatment of refractory benign colorectal anastomotic stricture |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7669833/ https://www.ncbi.nlm.nih.gov/pubmed/33199742 http://dx.doi.org/10.1038/s41598-020-76779-8 |
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