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Uncovered self-expandable metal stents for the treatment of refractory benign colorectal anastomotic stricture

Self-expandable metal stent (SEMS) placement has been suggested as a therapeutic modality for treating benign colorectal strictures. Covered stents are generally used, given the concerns regarding the efficacy and safety of uncovered stents. Hence, few studies have evaluated the efficacy and safety...

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Autores principales: Hong, Ji Taek, Kim, Tae Jun, Hong, Sung Noh, Kim, Young-Ho, Chang, Dong Kyung, Kim, Eun Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7669833/
https://www.ncbi.nlm.nih.gov/pubmed/33199742
http://dx.doi.org/10.1038/s41598-020-76779-8
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author Hong, Ji Taek
Kim, Tae Jun
Hong, Sung Noh
Kim, Young-Ho
Chang, Dong Kyung
Kim, Eun Ran
author_facet Hong, Ji Taek
Kim, Tae Jun
Hong, Sung Noh
Kim, Young-Ho
Chang, Dong Kyung
Kim, Eun Ran
author_sort Hong, Ji Taek
collection PubMed
description Self-expandable metal stent (SEMS) placement has been suggested as a therapeutic modality for treating benign colorectal strictures. Covered stents are generally used, given the concerns regarding the efficacy and safety of uncovered stents. Hence, few studies have evaluated the efficacy and safety of uncovered SEMSs (UCSEMSs) in patients with refractory benign colorectal anastomotic strictures. In this study, 12 patients with postoperative benign symptomatic anastomotic strictures refractory to pneumatic dilation (range, 2–9) and transient indwelling-covered SEMSs were treated using UCSEMS. All enrolled patients were men (mean age, 61 years). Stent placement was successful in all 12 patients, and early clinical success was achieved in 11 (92%) patients. Four patients (25%) showed successful clinical outcomes without further intervention, but eight patients (75%) were clinically unsuccessful, and showed stricture recurrence or functional obstructive symptoms. Three patients underwent surgery, and the remaining five patients required repeat stent procedures. Despite the high reobstruction rate, the median follow-up period after UCSEMS placement was 16.7 months, demonstrating that UCSEMS may be able to achieve medium-term symptom relief without any complications. Therefore, UCSEMS may be an alternative option in exceptional circumstances in carefully selected patients, where invasive surgical treatments, such as stoma diversion, are not an option, thereby improving patients’ quality of life.
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spelling pubmed-76698332020-11-18 Uncovered self-expandable metal stents for the treatment of refractory benign colorectal anastomotic stricture Hong, Ji Taek Kim, Tae Jun Hong, Sung Noh Kim, Young-Ho Chang, Dong Kyung Kim, Eun Ran Sci Rep Article Self-expandable metal stent (SEMS) placement has been suggested as a therapeutic modality for treating benign colorectal strictures. Covered stents are generally used, given the concerns regarding the efficacy and safety of uncovered stents. Hence, few studies have evaluated the efficacy and safety of uncovered SEMSs (UCSEMSs) in patients with refractory benign colorectal anastomotic strictures. In this study, 12 patients with postoperative benign symptomatic anastomotic strictures refractory to pneumatic dilation (range, 2–9) and transient indwelling-covered SEMSs were treated using UCSEMS. All enrolled patients were men (mean age, 61 years). Stent placement was successful in all 12 patients, and early clinical success was achieved in 11 (92%) patients. Four patients (25%) showed successful clinical outcomes without further intervention, but eight patients (75%) were clinically unsuccessful, and showed stricture recurrence or functional obstructive symptoms. Three patients underwent surgery, and the remaining five patients required repeat stent procedures. Despite the high reobstruction rate, the median follow-up period after UCSEMS placement was 16.7 months, demonstrating that UCSEMS may be able to achieve medium-term symptom relief without any complications. Therefore, UCSEMS may be an alternative option in exceptional circumstances in carefully selected patients, where invasive surgical treatments, such as stoma diversion, are not an option, thereby improving patients’ quality of life. Nature Publishing Group UK 2020-11-16 /pmc/articles/PMC7669833/ /pubmed/33199742 http://dx.doi.org/10.1038/s41598-020-76779-8 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Hong, Ji Taek
Kim, Tae Jun
Hong, Sung Noh
Kim, Young-Ho
Chang, Dong Kyung
Kim, Eun Ran
Uncovered self-expandable metal stents for the treatment of refractory benign colorectal anastomotic stricture
title Uncovered self-expandable metal stents for the treatment of refractory benign colorectal anastomotic stricture
title_full Uncovered self-expandable metal stents for the treatment of refractory benign colorectal anastomotic stricture
title_fullStr Uncovered self-expandable metal stents for the treatment of refractory benign colorectal anastomotic stricture
title_full_unstemmed Uncovered self-expandable metal stents for the treatment of refractory benign colorectal anastomotic stricture
title_short Uncovered self-expandable metal stents for the treatment of refractory benign colorectal anastomotic stricture
title_sort uncovered self-expandable metal stents for the treatment of refractory benign colorectal anastomotic stricture
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7669833/
https://www.ncbi.nlm.nih.gov/pubmed/33199742
http://dx.doi.org/10.1038/s41598-020-76779-8
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