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Risk of yellow fever virus transmission in the Asia-Pacific region
Historically endemic to Sub-Saharan Africa and South America, yellow fever is absent from the Asia-Pacific region. Yellow fever virus (YFV) is mainly transmitted by the anthropophilic Aedes mosquitoes whose distribution encompasses a large belt of tropical and sub tropical regions. Increasing exchan...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7669885/ https://www.ncbi.nlm.nih.gov/pubmed/33199712 http://dx.doi.org/10.1038/s41467-020-19625-9 |
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author | Lataillade, Lucy de Guilhem de Vazeille, Marie Obadia, Thomas Madec, Yoann Mousson, Laurence Kamgang, Basile Chen, Chun-Hong Failloux, Anna-Bella Yen, Pei-Shi |
author_facet | Lataillade, Lucy de Guilhem de Vazeille, Marie Obadia, Thomas Madec, Yoann Mousson, Laurence Kamgang, Basile Chen, Chun-Hong Failloux, Anna-Bella Yen, Pei-Shi |
author_sort | Lataillade, Lucy de Guilhem de |
collection | PubMed |
description | Historically endemic to Sub-Saharan Africa and South America, yellow fever is absent from the Asia-Pacific region. Yellow fever virus (YFV) is mainly transmitted by the anthropophilic Aedes mosquitoes whose distribution encompasses a large belt of tropical and sub tropical regions. Increasing exchanges between Africa and Asia have caused imported YFV incidents in non-endemic areas, which are threatening Asia with a new viral emergence. Here, using experimental infections of field-collected mosquitoes, we show that Asian-Pacific Aedes mosquitoes are competent vectors for YFV. We observe that Aedes aegypti populations from Singapore, Taiwan, Thailand, and New Caledonia are capable of transmitting YFV 14 days after oral infections, with a number of viral particles excreted from saliva reaching up to 23,000 viral particles. These findings represent the most comprehensive assessment of vector competence and show that Ae. aegypti mosquitoes from the Asia-Pacific region are highly competent to YFV, corroborating that vector populations are seemingly not a brake to the emergence of yellow fever in the region. |
format | Online Article Text |
id | pubmed-7669885 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-76698852020-11-24 Risk of yellow fever virus transmission in the Asia-Pacific region Lataillade, Lucy de Guilhem de Vazeille, Marie Obadia, Thomas Madec, Yoann Mousson, Laurence Kamgang, Basile Chen, Chun-Hong Failloux, Anna-Bella Yen, Pei-Shi Nat Commun Article Historically endemic to Sub-Saharan Africa and South America, yellow fever is absent from the Asia-Pacific region. Yellow fever virus (YFV) is mainly transmitted by the anthropophilic Aedes mosquitoes whose distribution encompasses a large belt of tropical and sub tropical regions. Increasing exchanges between Africa and Asia have caused imported YFV incidents in non-endemic areas, which are threatening Asia with a new viral emergence. Here, using experimental infections of field-collected mosquitoes, we show that Asian-Pacific Aedes mosquitoes are competent vectors for YFV. We observe that Aedes aegypti populations from Singapore, Taiwan, Thailand, and New Caledonia are capable of transmitting YFV 14 days after oral infections, with a number of viral particles excreted from saliva reaching up to 23,000 viral particles. These findings represent the most comprehensive assessment of vector competence and show that Ae. aegypti mosquitoes from the Asia-Pacific region are highly competent to YFV, corroborating that vector populations are seemingly not a brake to the emergence of yellow fever in the region. Nature Publishing Group UK 2020-11-16 /pmc/articles/PMC7669885/ /pubmed/33199712 http://dx.doi.org/10.1038/s41467-020-19625-9 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Lataillade, Lucy de Guilhem de Vazeille, Marie Obadia, Thomas Madec, Yoann Mousson, Laurence Kamgang, Basile Chen, Chun-Hong Failloux, Anna-Bella Yen, Pei-Shi Risk of yellow fever virus transmission in the Asia-Pacific region |
title | Risk of yellow fever virus transmission in the Asia-Pacific region |
title_full | Risk of yellow fever virus transmission in the Asia-Pacific region |
title_fullStr | Risk of yellow fever virus transmission in the Asia-Pacific region |
title_full_unstemmed | Risk of yellow fever virus transmission in the Asia-Pacific region |
title_short | Risk of yellow fever virus transmission in the Asia-Pacific region |
title_sort | risk of yellow fever virus transmission in the asia-pacific region |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7669885/ https://www.ncbi.nlm.nih.gov/pubmed/33199712 http://dx.doi.org/10.1038/s41467-020-19625-9 |
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