Multi-Responsive Silk Fibroin-Based Nanoparticles for Drug Delivery

Silk fibroin has the merits of biocompatibility, biodegradability, ease of processing, and feasibility of modification, which present it as a promising drug delivery material. This review focuses on the structures of silk fibroin, the controlled transformation of secondary structures, and the format...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Ya, Canup, Brandon S. B., Tong, Xiaoling, Dai, Fangyin, Xiao, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670059/
https://www.ncbi.nlm.nih.gov/pubmed/33240846
http://dx.doi.org/10.3389/fchem.2020.585077
_version_ 1783610662665060352
author Ma, Ya
Canup, Brandon S. B.
Tong, Xiaoling
Dai, Fangyin
Xiao, Bo
author_facet Ma, Ya
Canup, Brandon S. B.
Tong, Xiaoling
Dai, Fangyin
Xiao, Bo
author_sort Ma, Ya
collection PubMed
description Silk fibroin has the merits of biocompatibility, biodegradability, ease of processing, and feasibility of modification, which present it as a promising drug delivery material. This review focuses on the structures of silk fibroin, the controlled transformation of secondary structures, and the formation mechanism of silk fibroin-based nanoparticles (SFNPs). We also discuss the intrinsic multi-responsive, surface functionalization, and transgenic modification of SFNPs for drug delivery.
format Online
Article
Text
id pubmed-7670059
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-76700592020-11-24 Multi-Responsive Silk Fibroin-Based Nanoparticles for Drug Delivery Ma, Ya Canup, Brandon S. B. Tong, Xiaoling Dai, Fangyin Xiao, Bo Front Chem Chemistry Silk fibroin has the merits of biocompatibility, biodegradability, ease of processing, and feasibility of modification, which present it as a promising drug delivery material. This review focuses on the structures of silk fibroin, the controlled transformation of secondary structures, and the formation mechanism of silk fibroin-based nanoparticles (SFNPs). We also discuss the intrinsic multi-responsive, surface functionalization, and transgenic modification of SFNPs for drug delivery. Frontiers Media S.A. 2020-11-03 /pmc/articles/PMC7670059/ /pubmed/33240846 http://dx.doi.org/10.3389/fchem.2020.585077 Text en Copyright © 2020 Ma, Canup, Tong, Dai and Xiao. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Chemistry
Ma, Ya
Canup, Brandon S. B.
Tong, Xiaoling
Dai, Fangyin
Xiao, Bo
Multi-Responsive Silk Fibroin-Based Nanoparticles for Drug Delivery
title Multi-Responsive Silk Fibroin-Based Nanoparticles for Drug Delivery
title_full Multi-Responsive Silk Fibroin-Based Nanoparticles for Drug Delivery
title_fullStr Multi-Responsive Silk Fibroin-Based Nanoparticles for Drug Delivery
title_full_unstemmed Multi-Responsive Silk Fibroin-Based Nanoparticles for Drug Delivery
title_short Multi-Responsive Silk Fibroin-Based Nanoparticles for Drug Delivery
title_sort multi-responsive silk fibroin-based nanoparticles for drug delivery
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670059/
https://www.ncbi.nlm.nih.gov/pubmed/33240846
http://dx.doi.org/10.3389/fchem.2020.585077
work_keys_str_mv AT maya multiresponsivesilkfibroinbasednanoparticlesfordrugdelivery
AT canupbrandonsb multiresponsivesilkfibroinbasednanoparticlesfordrugdelivery
AT tongxiaoling multiresponsivesilkfibroinbasednanoparticlesfordrugdelivery
AT daifangyin multiresponsivesilkfibroinbasednanoparticlesfordrugdelivery
AT xiaobo multiresponsivesilkfibroinbasednanoparticlesfordrugdelivery

Ejemplares similares