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TNFAIP3 Plays a Role in Aging of the Hematopoietic System

Hematopoietic stem and progenitor cells (HSPC) experience a functional decline in response to chronic inflammation or aging. Haploinsufficiency of A20, or TNFAIP3, an innate immune regulator, is associated with a variety of autoimmune, inflammatory, and hematologic malignancies. Based on a prior ana...

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Detalles Bibliográficos
Autores principales:	Smith, Molly A., Culver-Cochran, Ashley E., Adelman, Emmalee R., Rhyasen, Garrett W., Ma, Averil, Figueroa, Maria E., Starczynowski, Daniel T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670064/ https://www.ncbi.nlm.nih.gov/pubmed/33224133 http://dx.doi.org/10.3389/fimmu.2020.536442

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