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Photoreceptor Degeneration in Pro23His Transgenic Rats (Line 3) Involves Autophagic and Necroptotic Mechanisms

Photoreceptor death contributes to 50% of irreversible vision loss in the western world. Pro23His (P23H) transgenic albino rat strains are widely used models for the most common rhodopsin gene mutation associated with the autosomal dominant form of retinitis pigmentosa. However, the mechanism(s) by...

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Detalles Bibliográficos
Autores principales:	Kakavand, Kiana, Jobling, Andrew I., Greferath, Ursula, Vessey, Kirstan A., de Iongh, Robb U., Fletcher, Erica L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670078/ https://www.ncbi.nlm.nih.gov/pubmed/33224023 http://dx.doi.org/10.3389/fnins.2020.581579

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