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Discovery of C—C bond-forming and bond-breaking radical enzymes: enabling transformations for metabolic engineering

Radical enzymes catalyze some of the most chemically challenging C—C bond-forming and bond-breaking reactions. Advances in DNA sequencing have accelerated the discovery of radical enzymes from microbes, including radical S-adenosylmethionine (rSAM) enzymes, glycyl radical enzymes (GREs), and diiron...

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Detalles Bibliográficos
Autores principales: Fu, Beverly, Balskus, Emily P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670169/
https://www.ncbi.nlm.nih.gov/pubmed/32171888
http://dx.doi.org/10.1016/j.copbio.2020.02.003

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