Study of correlation between epicardial fat thickness and severity of coronary artery disease

Epicardial fat thickness (EFT) reflects visceral adiposity and is associated with coronary artery disease (CAD). This study aimed to assess the correlation of echocardiographic EFT with the severity of CAD and to determine the EFT cut-off to predict CAD. EFT was measured in 503 patients undergoing c...

Descripción completa

Detalles Bibliográficos
Autores principales: Shambu, Sunil Kumar, Desai, Nagaraj, Sundaresh, Nikhil, Babu, M. Suresh, Madhu, B., Gona, Oliver Joel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Brief
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670255/
https://www.ncbi.nlm.nih.gov/pubmed/33189210
http://dx.doi.org/10.1016/j.ihj.2020.07.014
_version_ 1783610704071229440
author Shambu, Sunil Kumar
Desai, Nagaraj
Sundaresh, Nikhil
Babu, M. Suresh
Madhu, B.
Gona, Oliver Joel
author_facet Shambu, Sunil Kumar
Desai, Nagaraj
Sundaresh, Nikhil
Babu, M. Suresh
Madhu, B.
Gona, Oliver Joel
author_sort Shambu, Sunil Kumar
collection PubMed
description Epicardial fat thickness (EFT) reflects visceral adiposity and is associated with coronary artery disease (CAD). This study aimed to assess the correlation of echocardiographic EFT with the severity of CAD and to determine the EFT cut-off to predict CAD. EFT was measured in 503 patients undergoing coronary angiogram. Mean EFT was significantly higher in the CAD group than control group (5.55 ± 1.21 mm vs 3.25 ± 1.15 mm, p < 0.0001). EFT correlated with Gensini score (r = 0.906, p < 0.001). EFT cut-off ≥ 4.75 mm had 87% sensitivity and 63% specificity for prediction of significant CAD (AUC: 0.831, p < 0.001).
format Online
Article
Text
id pubmed-7670255
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-76702552020-11-23 Study of correlation between epicardial fat thickness and severity of coronary artery disease Shambu, Sunil Kumar Desai, Nagaraj Sundaresh, Nikhil Babu, M. Suresh Madhu, B. Gona, Oliver Joel Indian Heart J Research Brief Epicardial fat thickness (EFT) reflects visceral adiposity and is associated with coronary artery disease (CAD). This study aimed to assess the correlation of echocardiographic EFT with the severity of CAD and to determine the EFT cut-off to predict CAD. EFT was measured in 503 patients undergoing coronary angiogram. Mean EFT was significantly higher in the CAD group than control group (5.55 ± 1.21 mm vs 3.25 ± 1.15 mm, p < 0.0001). EFT correlated with Gensini score (r = 0.906, p < 0.001). EFT cut-off ≥ 4.75 mm had 87% sensitivity and 63% specificity for prediction of significant CAD (AUC: 0.831, p < 0.001). Elsevier 2020 2020-07-17 /pmc/articles/PMC7670255/ /pubmed/33189210 http://dx.doi.org/10.1016/j.ihj.2020.07.014 Text en © 2020 Cardiological Society of India. Published by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Research Brief
Shambu, Sunil Kumar
Desai, Nagaraj
Sundaresh, Nikhil
Babu, M. Suresh
Madhu, B.
Gona, Oliver Joel
Study of correlation between epicardial fat thickness and severity of coronary artery disease
title Study of correlation between epicardial fat thickness and severity of coronary artery disease
title_full Study of correlation between epicardial fat thickness and severity of coronary artery disease
title_fullStr Study of correlation between epicardial fat thickness and severity of coronary artery disease
title_full_unstemmed Study of correlation between epicardial fat thickness and severity of coronary artery disease
title_short Study of correlation between epicardial fat thickness and severity of coronary artery disease
title_sort study of correlation between epicardial fat thickness and severity of coronary artery disease
topic Research Brief
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670255/
https://www.ncbi.nlm.nih.gov/pubmed/33189210
http://dx.doi.org/10.1016/j.ihj.2020.07.014
work_keys_str_mv AT shambusunilkumar studyofcorrelationbetweenepicardialfatthicknessandseverityofcoronaryarterydisease
AT desainagaraj studyofcorrelationbetweenepicardialfatthicknessandseverityofcoronaryarterydisease
AT sundareshnikhil studyofcorrelationbetweenepicardialfatthicknessandseverityofcoronaryarterydisease
AT babumsuresh studyofcorrelationbetweenepicardialfatthicknessandseverityofcoronaryarterydisease
AT madhub studyofcorrelationbetweenepicardialfatthicknessandseverityofcoronaryarterydisease
AT gonaoliverjoel studyofcorrelationbetweenepicardialfatthicknessandseverityofcoronaryarterydisease

Ejemplares similares