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Combined Influence of Waist and Hip Circumference on Risk of Death in a Large Cohort of European and Australian Adults
BACKGROUND: Waist circumference and hip circumference are both strongly associated with risk of death; however, their joint association has rarely been investigated. METHODS AND RESULTS: The MONICA Risk, Genetics, Archiving, and Monograph (MORGAM) Project was conducted in 30 cohorts from 11 countrie...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670538/ https://www.ncbi.nlm.nih.gov/pubmed/32602397 http://dx.doi.org/10.1161/JAHA.119.015189 |
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author | Cameron, Adrian J. Romaniuk, Helena Orellana, Liliana Dallongeville, Jean Dobson, Annette J. Drygas, Wojciech Ferrario, Marco Ferrieres, Jean Giampaoli, Simona Gianfagna, Francesco Iacoviello, Licia Jousilahti, Pekka Kee, Frank Moitry, Marie Niiranen, Teemu J. Pająk, Andrzej Palmieri, Luigi Palosaari, Tarja Satu, Männistö Tamosiunas, Abdonas Thorand, Barbara Toft, Ulla Vanuzzo, Diego Veikko, Salomaa Veronesi, Giovanni Wilsgaard, Tom Kuulasmaa, Kari Söderberg, Stefan |
author_facet | Cameron, Adrian J. Romaniuk, Helena Orellana, Liliana Dallongeville, Jean Dobson, Annette J. Drygas, Wojciech Ferrario, Marco Ferrieres, Jean Giampaoli, Simona Gianfagna, Francesco Iacoviello, Licia Jousilahti, Pekka Kee, Frank Moitry, Marie Niiranen, Teemu J. Pająk, Andrzej Palmieri, Luigi Palosaari, Tarja Satu, Männistö Tamosiunas, Abdonas Thorand, Barbara Toft, Ulla Vanuzzo, Diego Veikko, Salomaa Veronesi, Giovanni Wilsgaard, Tom Kuulasmaa, Kari Söderberg, Stefan |
author_sort | Cameron, Adrian J. |
collection | PubMed |
description | BACKGROUND: Waist circumference and hip circumference are both strongly associated with risk of death; however, their joint association has rarely been investigated. METHODS AND RESULTS: The MONICA Risk, Genetics, Archiving, and Monograph (MORGAM) Project was conducted in 30 cohorts from 11 countries; 90 487 men and women, aged 30 to 74 years, predominantly white, with no history of cardiovascular disease, were recruited in 1986 to 2010 and followed up for up to 24 years. Hazard ratios were estimated using sex‐specific Cox models, stratified by cohort, with age as the time scale. Models included baseline categorical obesity measures, age, total and high‐density lipoprotein cholesterol, systolic blood pressure, antihypertensive drugs, smoking, and diabetes mellitus. A total of 9105 all‐cause deaths were recorded during a median follow‐up of 10 years. Hazard ratios for all‐cause death presented J‐ or U‐shaped associations with most obesity measures. With waist and hip circumference included in the same model, for all hip sizes, having a smaller waist was strongly associated with lower risk of death, except for men with the smallest hips. In addition, among those with smaller waists, hip size was strongly negatively associated with risk of death, with ≈20% more people identified as being at increased risk compared with waist circumference alone. CONCLUSIONS: A more complex relationship between hip circumference, waist circumference, and risk of death is revealed when both measures are considered simultaneously. This is particularly true for individuals with smaller waists, where having larger hips was protective. Considering both waist and hip circumference in the clinical setting could help to best identify those at increased risk of death. |
format | Online Article Text |
id | pubmed-7670538 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-76705382020-11-23 Combined Influence of Waist and Hip Circumference on Risk of Death in a Large Cohort of European and Australian Adults Cameron, Adrian J. Romaniuk, Helena Orellana, Liliana Dallongeville, Jean Dobson, Annette J. Drygas, Wojciech Ferrario, Marco Ferrieres, Jean Giampaoli, Simona Gianfagna, Francesco Iacoviello, Licia Jousilahti, Pekka Kee, Frank Moitry, Marie Niiranen, Teemu J. Pająk, Andrzej Palmieri, Luigi Palosaari, Tarja Satu, Männistö Tamosiunas, Abdonas Thorand, Barbara Toft, Ulla Vanuzzo, Diego Veikko, Salomaa Veronesi, Giovanni Wilsgaard, Tom Kuulasmaa, Kari Söderberg, Stefan J Am Heart Assoc Original Research BACKGROUND: Waist circumference and hip circumference are both strongly associated with risk of death; however, their joint association has rarely been investigated. METHODS AND RESULTS: The MONICA Risk, Genetics, Archiving, and Monograph (MORGAM) Project was conducted in 30 cohorts from 11 countries; 90 487 men and women, aged 30 to 74 years, predominantly white, with no history of cardiovascular disease, were recruited in 1986 to 2010 and followed up for up to 24 years. Hazard ratios were estimated using sex‐specific Cox models, stratified by cohort, with age as the time scale. Models included baseline categorical obesity measures, age, total and high‐density lipoprotein cholesterol, systolic blood pressure, antihypertensive drugs, smoking, and diabetes mellitus. A total of 9105 all‐cause deaths were recorded during a median follow‐up of 10 years. Hazard ratios for all‐cause death presented J‐ or U‐shaped associations with most obesity measures. With waist and hip circumference included in the same model, for all hip sizes, having a smaller waist was strongly associated with lower risk of death, except for men with the smallest hips. In addition, among those with smaller waists, hip size was strongly negatively associated with risk of death, with ≈20% more people identified as being at increased risk compared with waist circumference alone. CONCLUSIONS: A more complex relationship between hip circumference, waist circumference, and risk of death is revealed when both measures are considered simultaneously. This is particularly true for individuals with smaller waists, where having larger hips was protective. Considering both waist and hip circumference in the clinical setting could help to best identify those at increased risk of death. John Wiley and Sons Inc. 2020-06-30 /pmc/articles/PMC7670538/ /pubmed/32602397 http://dx.doi.org/10.1161/JAHA.119.015189 Text en © 2020 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Original Research Cameron, Adrian J. Romaniuk, Helena Orellana, Liliana Dallongeville, Jean Dobson, Annette J. Drygas, Wojciech Ferrario, Marco Ferrieres, Jean Giampaoli, Simona Gianfagna, Francesco Iacoviello, Licia Jousilahti, Pekka Kee, Frank Moitry, Marie Niiranen, Teemu J. Pająk, Andrzej Palmieri, Luigi Palosaari, Tarja Satu, Männistö Tamosiunas, Abdonas Thorand, Barbara Toft, Ulla Vanuzzo, Diego Veikko, Salomaa Veronesi, Giovanni Wilsgaard, Tom Kuulasmaa, Kari Söderberg, Stefan Combined Influence of Waist and Hip Circumference on Risk of Death in a Large Cohort of European and Australian Adults |
title | Combined Influence of Waist and Hip Circumference on Risk of Death in a Large Cohort of European and Australian Adults |
title_full | Combined Influence of Waist and Hip Circumference on Risk of Death in a Large Cohort of European and Australian Adults |
title_fullStr | Combined Influence of Waist and Hip Circumference on Risk of Death in a Large Cohort of European and Australian Adults |
title_full_unstemmed | Combined Influence of Waist and Hip Circumference on Risk of Death in a Large Cohort of European and Australian Adults |
title_short | Combined Influence of Waist and Hip Circumference on Risk of Death in a Large Cohort of European and Australian Adults |
title_sort | combined influence of waist and hip circumference on risk of death in a large cohort of european and australian adults |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670538/ https://www.ncbi.nlm.nih.gov/pubmed/32602397 http://dx.doi.org/10.1161/JAHA.119.015189 |
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