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Widespread regulation of gene expression by glucocorticoids in chondrocytes from patients with osteoarthritis as determined by RNA-Seq

BACKGROUND: Intra-articular glucocorticoid (GC) injections are widely used as a symptomatic treatment for osteoarthritis (OA). However, there are also concerns about their potentially harmful effects, and their detailed effects on chondrocyte phenotype remain poorly understood. METHODS: We studied t...

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Detalles Bibliográficos
Autores principales: Pemmari, Antti, Leppänen, Tiina, Hämäläinen, Mari, Moilanen, Teemu, Vuolteenaho, Katriina, Moilanen, Eeva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670667/
https://www.ncbi.nlm.nih.gov/pubmed/33203447
http://dx.doi.org/10.1186/s13075-020-02289-7