HTLV-2 infection in Manaus, Brazil: first description of HTLV-2c subtype in an urban area of the Western Amazon region

INTRODUCTION: We investigated the prevalence of human T-cell lymphotropic virus types 1 and 2 (HTLV-1/2) infection in patients with hematological diseases from the western Amazon region of Brazil. METHODS: Samples from 306 patients were submitted for the molecular diagnosis of HTLV-1/2 infection by...

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Autores principales: Pontes, Gemilson Soares, Ribeiro, Hygor Halyson Figueiredo, Toro, Diana Mota, de Moura, José Pereira, Souza, Victor, de Almeida, Maria Edilene Martins, do Nascimento, Valdinete Alves, da Costa, Cristovão Alves, Naveca, Felipe Gomes, Santos, Mike, Vallinoto, Antonio Carlos Rosário
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Medicina Tropical - SBMT 2020
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670738/
https://www.ncbi.nlm.nih.gov/pubmed/33206874
http://dx.doi.org/10.1590/0037-8682-0066-2020
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author Pontes, Gemilson Soares
Ribeiro, Hygor Halyson Figueiredo
Toro, Diana Mota
de Moura, José Pereira
Souza, Victor
de Almeida, Maria Edilene Martins
do Nascimento, Valdinete Alves
da Costa, Cristovão Alves
Naveca, Felipe Gomes
Santos, Mike
Vallinoto, Antonio Carlos Rosário
author_facet Pontes, Gemilson Soares
Ribeiro, Hygor Halyson Figueiredo
Toro, Diana Mota
de Moura, José Pereira
Souza, Victor
de Almeida, Maria Edilene Martins
do Nascimento, Valdinete Alves
da Costa, Cristovão Alves
Naveca, Felipe Gomes
Santos, Mike
Vallinoto, Antonio Carlos Rosário
author_sort Pontes, Gemilson Soares
collection PubMed
description INTRODUCTION: We investigated the prevalence of human T-cell lymphotropic virus types 1 and 2 (HTLV-1/2) infection in patients with hematological diseases from the western Amazon region of Brazil. METHODS: Samples from 306 patients were submitted for the molecular diagnosis of HTLV-1/2 infection by real time PCR (qPCR), with amplification, sequencing, and phylogenetic analysis of the long terminal repeat (LTR) region. RESULTS: A 29-year-old male carrier of sickle cell anemia with a history of multiple blood transfusions was diagnosed with the HTLV-2c subtype. CONCLUSIONS: This study describes the first known occurrence of HTLV-2c in the urban area of Brazil’s western Amazon region.
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spelling pubmed-76707382020-11-18 HTLV-2 infection in Manaus, Brazil: first description of HTLV-2c subtype in an urban area of the Western Amazon region Pontes, Gemilson Soares Ribeiro, Hygor Halyson Figueiredo Toro, Diana Mota de Moura, José Pereira Souza, Victor de Almeida, Maria Edilene Martins do Nascimento, Valdinete Alves da Costa, Cristovão Alves Naveca, Felipe Gomes Santos, Mike Vallinoto, Antonio Carlos Rosário Rev Soc Bras Med Trop Short Communication INTRODUCTION: We investigated the prevalence of human T-cell lymphotropic virus types 1 and 2 (HTLV-1/2) infection in patients with hematological diseases from the western Amazon region of Brazil. METHODS: Samples from 306 patients were submitted for the molecular diagnosis of HTLV-1/2 infection by real time PCR (qPCR), with amplification, sequencing, and phylogenetic analysis of the long terminal repeat (LTR) region. RESULTS: A 29-year-old male carrier of sickle cell anemia with a history of multiple blood transfusions was diagnosed with the HTLV-2c subtype. CONCLUSIONS: This study describes the first known occurrence of HTLV-2c in the urban area of Brazil’s western Amazon region. Sociedade Brasileira de Medicina Tropical - SBMT 2020-11-13 /pmc/articles/PMC7670738/ /pubmed/33206874 http://dx.doi.org/10.1590/0037-8682-0066-2020 Text en https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Short Communication
Pontes, Gemilson Soares
Ribeiro, Hygor Halyson Figueiredo
Toro, Diana Mota
de Moura, José Pereira
Souza, Victor
de Almeida, Maria Edilene Martins
do Nascimento, Valdinete Alves
da Costa, Cristovão Alves
Naveca, Felipe Gomes
Santos, Mike
Vallinoto, Antonio Carlos Rosário
HTLV-2 infection in Manaus, Brazil: first description of HTLV-2c subtype in an urban area of the Western Amazon region
title HTLV-2 infection in Manaus, Brazil: first description of HTLV-2c subtype in an urban area of the Western Amazon region
title_full HTLV-2 infection in Manaus, Brazil: first description of HTLV-2c subtype in an urban area of the Western Amazon region
title_fullStr HTLV-2 infection in Manaus, Brazil: first description of HTLV-2c subtype in an urban area of the Western Amazon region
title_full_unstemmed HTLV-2 infection in Manaus, Brazil: first description of HTLV-2c subtype in an urban area of the Western Amazon region
title_short HTLV-2 infection in Manaus, Brazil: first description of HTLV-2c subtype in an urban area of the Western Amazon region
title_sort htlv-2 infection in manaus, brazil: first description of htlv-2c subtype in an urban area of the western amazon region
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670738/
https://www.ncbi.nlm.nih.gov/pubmed/33206874
http://dx.doi.org/10.1590/0037-8682-0066-2020
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