First report of the aac(6’)-Ib-cr gene in Providencia stuartii isolates in Brazil

INTRODUCTION: The aac(6’)-Ib-cr and bla (KPC) genes are spreading among Enterobacteriaceae species, including Providencia stuartii, in some countries of world. METHODS: These genes were investigated in 28 P. stuartii isolates from a public hospital in Recife, Pernambuco, Brazil, by PCR and sequencin...

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Detalles Bibliográficos
Autores principales: da Silva, Sivoneide Maria, Ramos, Bárbara de Azevedo, Lima, Ana Vitória Araújo, de Sá, Rafael Artur Cavalcanti Queiroz, Lima, Jailton Lobo da Costa, Maciel, Maria Amélia Vieira, Paiva, Patrícia Maria Guedes, da Silva, Márcia Vanusa, Correia, Maria Tereza dos Santos, de Oliveira, Maria Betânia Melo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Medicina Tropical - SBMT 2020
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670762/
https://www.ncbi.nlm.nih.gov/pubmed/33206872
http://dx.doi.org/10.1590/0037-8682-0524-2019
Descripción
Sumario:INTRODUCTION: The aac(6’)-Ib-cr and bla (KPC) genes are spreading among Enterobacteriaceae species, including Providencia stuartii, in some countries of world. METHODS: These genes were investigated in 28 P. stuartii isolates from a public hospital in Recife, Pernambuco, Brazil, by PCR and sequencing. RESULTS: The aac(6’)-Ib-cr gene was detected in 16 resistant isolates, and the bla (KPC) gene was seen in 14. CONCLUSIONS: The presence of these genes in P. stuartii multi- and extensively drug-resistant isolates indicates that the resistance arsenal of this species is increasing, thus limiting the therapeutic options.

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