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Juvenile idiopathic arthritis fibroblast-like synoviocytes influence chondrocytes to alter BMP antagonist expression demonstrating an interaction between the two prominent cell types involved in endochondral bone formation

BACKGROUND: To examine critical interactions between juvenile idiopathic arthritis synovial fibroblasts (JFLS) and chondrocytes (Ch), and their role in bony overgrowth seen in patients with juvenile idiopathic arthritis (JIA). METHODS: Control (CFLS) and JFLS were cultured in synoviocyte media conta...

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Detalles Bibliográficos
Autores principales:	Simonds, Megan M., Schlefman, Amanda R., McCahan, Suzanne M., Sullivan, Kathleen E., Rose, Carlos D., Brescia, AnneMarie C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670793/ https://www.ncbi.nlm.nih.gov/pubmed/33198759 http://dx.doi.org/10.1186/s12969-020-00483-0

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