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Rare case of COVID-19 presenting as acute abdomen and sepsis

Coronavirus disease 2019 (COVID-19) may present as acute abdomen, although the pathophysiology remains obscure. We report the case of a 45-year-old-man with severe COVID-19 pneumonia with associated pulmonary embolism who presented with acute abdomen. He underwent emergency laparotomy and resection...

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Autores principales: Alharthy, A., Balhamar, A., Faqihi, F., Nasim, N., Noor, A.F., Alqahtani, S.A., Memish, Z.A., Karakitsos, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670919/
https://www.ncbi.nlm.nih.gov/pubmed/33224507
http://dx.doi.org/10.1016/j.nmni.2020.100818
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author Alharthy, A.
Balhamar, A.
Faqihi, F.
Nasim, N.
Noor, A.F.
Alqahtani, S.A.
Memish, Z.A.
Karakitsos, D.
author_facet Alharthy, A.
Balhamar, A.
Faqihi, F.
Nasim, N.
Noor, A.F.
Alqahtani, S.A.
Memish, Z.A.
Karakitsos, D.
author_sort Alharthy, A.
collection PubMed
description Coronavirus disease 2019 (COVID-19) may present as acute abdomen, although the pathophysiology remains obscure. We report the case of a 45-year-old-man with severe COVID-19 pneumonia with associated pulmonary embolism who presented with acute abdomen. He underwent emergency laparotomy and resection of an ischaemic area of the jejunum. Postoperatively, he had septic shock, acute respiratory distress syndrome and acute kidney injury necessitating continuous renal replacement therapy. We administered antibiotics and therapeutic anticoagulation along with two sessions of haemoadsorption by CytoSorb filter, in conjunction with continuous renal replacement therapy. The patient survived. Bowel ischaemia due to thromboembolic disease should be promptly treated. Extracorporeal blood purification may be useful in managing sepsis in severe COVID-19.
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spelling pubmed-76709192020-11-18 Rare case of COVID-19 presenting as acute abdomen and sepsis Alharthy, A. Balhamar, A. Faqihi, F. Nasim, N. Noor, A.F. Alqahtani, S.A. Memish, Z.A. Karakitsos, D. New Microbes New Infect New Microbes in Humans Coronavirus disease 2019 (COVID-19) may present as acute abdomen, although the pathophysiology remains obscure. We report the case of a 45-year-old-man with severe COVID-19 pneumonia with associated pulmonary embolism who presented with acute abdomen. He underwent emergency laparotomy and resection of an ischaemic area of the jejunum. Postoperatively, he had septic shock, acute respiratory distress syndrome and acute kidney injury necessitating continuous renal replacement therapy. We administered antibiotics and therapeutic anticoagulation along with two sessions of haemoadsorption by CytoSorb filter, in conjunction with continuous renal replacement therapy. The patient survived. Bowel ischaemia due to thromboembolic disease should be promptly treated. Extracorporeal blood purification may be useful in managing sepsis in severe COVID-19. Elsevier 2020-11-17 /pmc/articles/PMC7670919/ /pubmed/33224507 http://dx.doi.org/10.1016/j.nmni.2020.100818 Text en © 2020 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle New Microbes in Humans
Alharthy, A.
Balhamar, A.
Faqihi, F.
Nasim, N.
Noor, A.F.
Alqahtani, S.A.
Memish, Z.A.
Karakitsos, D.
Rare case of COVID-19 presenting as acute abdomen and sepsis
title Rare case of COVID-19 presenting as acute abdomen and sepsis
title_full Rare case of COVID-19 presenting as acute abdomen and sepsis
title_fullStr Rare case of COVID-19 presenting as acute abdomen and sepsis
title_full_unstemmed Rare case of COVID-19 presenting as acute abdomen and sepsis
title_short Rare case of COVID-19 presenting as acute abdomen and sepsis
title_sort rare case of covid-19 presenting as acute abdomen and sepsis
topic New Microbes in Humans
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670919/
https://www.ncbi.nlm.nih.gov/pubmed/33224507
http://dx.doi.org/10.1016/j.nmni.2020.100818
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