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A new chapter in the CD8 T reg story
CD8(+) T reg cells play an important role in the maintenance of self-tolerance and can inhibit the development of autoimmune disease. In this issue of JEM, Mishra et al. (https://doi.org/10.1084/jem.20200030) reveal that TGF-β signaling and an Eomes-dependent genetic program contribute to CD8 T reg...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670959/ https://www.ncbi.nlm.nih.gov/pubmed/33180093 http://dx.doi.org/10.1084/jem.20201746 |
| _version_ | 1783610841861455872 |
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| author | Cantor, Harvey Kim, Hye-Jung |
| author_facet | Cantor, Harvey Kim, Hye-Jung |
| author_sort | Cantor, Harvey |
| collection | PubMed |
| description | CD8(+) T reg cells play an important role in the maintenance of self-tolerance and can inhibit the development of autoimmune disease. In this issue of JEM, Mishra et al. (https://doi.org/10.1084/jem.20200030) reveal that TGF-β signaling and an Eomes-dependent genetic program contribute to CD8 T reg cell differentiation and function. |
| format | Online Article Text |
| id | pubmed-7670959 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2020 |
| publisher | Rockefeller University Press |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-76709592021-07-04 A new chapter in the CD8 T reg story Cantor, Harvey Kim, Hye-Jung J Exp Med Insights CD8(+) T reg cells play an important role in the maintenance of self-tolerance and can inhibit the development of autoimmune disease. In this issue of JEM, Mishra et al. (https://doi.org/10.1084/jem.20200030) reveal that TGF-β signaling and an Eomes-dependent genetic program contribute to CD8 T reg cell differentiation and function. Rockefeller University Press 2020-11-12 /pmc/articles/PMC7670959/ /pubmed/33180093 http://dx.doi.org/10.1084/jem.20201746 Text en © 2020 Cantor and Kim http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/). |
| spellingShingle | Insights Cantor, Harvey Kim, Hye-Jung A new chapter in the CD8 T reg story |
| title | A new chapter in the CD8 T reg story |
| title_full | A new chapter in the CD8 T reg story |
| title_fullStr | A new chapter in the CD8 T reg story |
| title_full_unstemmed | A new chapter in the CD8 T reg story |
| title_short | A new chapter in the CD8 T reg story |
| title_sort | new chapter in the cd8 t reg story |
| topic | Insights |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670959/ https://www.ncbi.nlm.nih.gov/pubmed/33180093 http://dx.doi.org/10.1084/jem.20201746 |
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