Sometimes even apoptosis fails: implications for cancer

Apoptosis is vital for the correct morphogenesis of multi-cellular organisms. However, like most physiological programs, the cell’s ability to commit suicide is hijacked by cancer in its own proliferative and invasive interest. We recently showed that inefficient execution of apoptosis (or failed ap...

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Detalles Bibliográficos
Autores principales: Berthenet, Kevin, Weber, Kathrin, Ichim, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Author’s Views
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671000/
https://www.ncbi.nlm.nih.gov/pubmed/33235903
http://dx.doi.org/10.1080/23723556.2020.1797430
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author Berthenet, Kevin
Weber, Kathrin
Ichim, Gabriel
author_facet Berthenet, Kevin
Weber, Kathrin
Ichim, Gabriel
author_sort Berthenet, Kevin
collection PubMed
description Apoptosis is vital for the correct morphogenesis of multi-cellular organisms. However, like most physiological programs, the cell’s ability to commit suicide is hijacked by cancer in its own proliferative and invasive interest. We recently showed that inefficient execution of apoptosis (or failed apoptosis) is used by cancer to boost invasiveness.
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spelling pubmed-76710002020-11-23 Sometimes even apoptosis fails: implications for cancer Berthenet, Kevin Weber, Kathrin Ichim, Gabriel Mol Cell Oncol Author’s Views Apoptosis is vital for the correct morphogenesis of multi-cellular organisms. However, like most physiological programs, the cell’s ability to commit suicide is hijacked by cancer in its own proliferative and invasive interest. We recently showed that inefficient execution of apoptosis (or failed apoptosis) is used by cancer to boost invasiveness. Taylor & Francis 2020-08-23 /pmc/articles/PMC7671000/ /pubmed/33235903 http://dx.doi.org/10.1080/23723556.2020.1797430 Text en © 2020 The Author(s). Published with license by Taylor & Francis Group, LLC. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.
spellingShingle Author’s Views
Berthenet, Kevin
Weber, Kathrin
Ichim, Gabriel
Sometimes even apoptosis fails: implications for cancer
title Sometimes even apoptosis fails: implications for cancer
title_full Sometimes even apoptosis fails: implications for cancer
title_fullStr Sometimes even apoptosis fails: implications for cancer
title_full_unstemmed Sometimes even apoptosis fails: implications for cancer
title_short Sometimes even apoptosis fails: implications for cancer
title_sort sometimes even apoptosis fails: implications for cancer
topic Author’s Views
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671000/
https://www.ncbi.nlm.nih.gov/pubmed/33235903
http://dx.doi.org/10.1080/23723556.2020.1797430
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