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Unconventional role of RAC1 in MET-driven anchorage-independent tumor growth

We reported that RAC1 is a master regulator of cell migration and anchorage-independent growth, downstream of the oncogenic Receptor Tyrosine Kinase (RTK) MET. RAC1 growth-promoting role is guanosine triphosphatase (GTPase)- and phosphatidylinositol 3-kinase (PI3K)-independent but promotes mammalian...

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Detalles Bibliográficos
Autores principales:	Hervieu, Alexia, Kermorgant, Stéphanie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2020
Materias:	Author’s Views
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671004/ https://www.ncbi.nlm.nih.gov/pubmed/33235904 http://dx.doi.org/10.1080/23723556.2020.1803029

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