NG-Circos: next-generation Circos for data visualization and interpretation

Circos plots are widely used to display multi-dimensional next-generation genomic data, but existing implementations of Circos are not interactive with limited support of data types. Here, we developed next-generation Circos (NG-Circos), a flexible JavaScript-based circular genome visualization tool...

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Detalles Bibliográficos
Autores principales: Cui, Ya, Cui, Zhe, Xu, Jianfeng, Hao, Dapeng, Shi, Jiejun, Wang, Dan, Xiao, Hui, Duan, Xiaohong, Chen, Runsheng, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
APP Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671351/
https://www.ncbi.nlm.nih.gov/pubmed/33575618
http://dx.doi.org/10.1093/nargab/lqaa069
Descripción
Sumario:Circos plots are widely used to display multi-dimensional next-generation genomic data, but existing implementations of Circos are not interactive with limited support of data types. Here, we developed next-generation Circos (NG-Circos), a flexible JavaScript-based circular genome visualization tool for designing highly interactive Circos plots using 21 functional modules with various data types. To our knowledge, NG-Circos is the most powerful software to construct interactive Circos plots. By supporting diverse data types in a dynamic browser interface, NG-Circos will accelerate the next-generation data visualization and interpretation, thus promoting the reproducible research in biomedical sciences and beyond. NG-Circos is available at https://wlcb.oit.uci.edu/NG-Circos and https://github.com/YaCui/NG-Circos.

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