NG-Circos: next-generation Circos for data visualization and interpretation

Circos plots are widely used to display multi-dimensional next-generation genomic data, but existing implementations of Circos are not interactive with limited support of data types. Here, we developed next-generation Circos (NG-Circos), a flexible JavaScript-based circular genome visualization tool...

Descripción completa

Detalles Bibliográficos
Autores principales: Cui, Ya, Cui, Zhe, Xu, Jianfeng, Hao, Dapeng, Shi, Jiejun, Wang, Dan, Xiao, Hui, Duan, Xiaohong, Chen, Runsheng, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
APP Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671351/
https://www.ncbi.nlm.nih.gov/pubmed/33575618
http://dx.doi.org/10.1093/nargab/lqaa069
_version_ 1783610913020968960
author Cui, Ya
Cui, Zhe
Xu, Jianfeng
Hao, Dapeng
Shi, Jiejun
Wang, Dan
Xiao, Hui
Duan, Xiaohong
Chen, Runsheng
Li, Wei
author_facet Cui, Ya
Cui, Zhe
Xu, Jianfeng
Hao, Dapeng
Shi, Jiejun
Wang, Dan
Xiao, Hui
Duan, Xiaohong
Chen, Runsheng
Li, Wei
author_sort Cui, Ya
collection PubMed
description Circos plots are widely used to display multi-dimensional next-generation genomic data, but existing implementations of Circos are not interactive with limited support of data types. Here, we developed next-generation Circos (NG-Circos), a flexible JavaScript-based circular genome visualization tool for designing highly interactive Circos plots using 21 functional modules with various data types. To our knowledge, NG-Circos is the most powerful software to construct interactive Circos plots. By supporting diverse data types in a dynamic browser interface, NG-Circos will accelerate the next-generation data visualization and interpretation, thus promoting the reproducible research in biomedical sciences and beyond. NG-Circos is available at https://wlcb.oit.uci.edu/NG-Circos and https://github.com/YaCui/NG-Circos.
format Online
Article
Text
id pubmed-7671351
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-76713512021-02-10 NG-Circos: next-generation Circos for data visualization and interpretation Cui, Ya Cui, Zhe Xu, Jianfeng Hao, Dapeng Shi, Jiejun Wang, Dan Xiao, Hui Duan, Xiaohong Chen, Runsheng Li, Wei NAR Genom Bioinform APP Notes Circos plots are widely used to display multi-dimensional next-generation genomic data, but existing implementations of Circos are not interactive with limited support of data types. Here, we developed next-generation Circos (NG-Circos), a flexible JavaScript-based circular genome visualization tool for designing highly interactive Circos plots using 21 functional modules with various data types. To our knowledge, NG-Circos is the most powerful software to construct interactive Circos plots. By supporting diverse data types in a dynamic browser interface, NG-Circos will accelerate the next-generation data visualization and interpretation, thus promoting the reproducible research in biomedical sciences and beyond. NG-Circos is available at https://wlcb.oit.uci.edu/NG-Circos and https://github.com/YaCui/NG-Circos. Oxford University Press 2020-09-03 /pmc/articles/PMC7671351/ /pubmed/33575618 http://dx.doi.org/10.1093/nargab/lqaa069 Text en © The Author(s) 2019. Published by Oxford University Press on behalf of NAR Genomics and Bioinformatics. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle APP Notes
Cui, Ya
Cui, Zhe
Xu, Jianfeng
Hao, Dapeng
Shi, Jiejun
Wang, Dan
Xiao, Hui
Duan, Xiaohong
Chen, Runsheng
Li, Wei
NG-Circos: next-generation Circos for data visualization and interpretation
title NG-Circos: next-generation Circos for data visualization and interpretation
title_full NG-Circos: next-generation Circos for data visualization and interpretation
title_fullStr NG-Circos: next-generation Circos for data visualization and interpretation
title_full_unstemmed NG-Circos: next-generation Circos for data visualization and interpretation
title_short NG-Circos: next-generation Circos for data visualization and interpretation
title_sort ng-circos: next-generation circos for data visualization and interpretation
topic APP Notes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671351/
https://www.ncbi.nlm.nih.gov/pubmed/33575618
http://dx.doi.org/10.1093/nargab/lqaa069
work_keys_str_mv AT cuiya ngcircosnextgenerationcircosfordatavisualizationandinterpretation
AT cuizhe ngcircosnextgenerationcircosfordatavisualizationandinterpretation
AT xujianfeng ngcircosnextgenerationcircosfordatavisualizationandinterpretation
AT haodapeng ngcircosnextgenerationcircosfordatavisualizationandinterpretation
AT shijiejun ngcircosnextgenerationcircosfordatavisualizationandinterpretation
AT wangdan ngcircosnextgenerationcircosfordatavisualizationandinterpretation
AT xiaohui ngcircosnextgenerationcircosfordatavisualizationandinterpretation
AT duanxiaohong ngcircosnextgenerationcircosfordatavisualizationandinterpretation
AT chenrunsheng ngcircosnextgenerationcircosfordatavisualizationandinterpretation
AT liwei ngcircosnextgenerationcircosfordatavisualizationandinterpretation

Ejemplares similares