Authentication, characterization and contamination detection of cell lines, xenografts and organoids by barcode deep NGS sequencing

Misidentification and contamination of biobank samples (e.g. cell lines) have plagued biomedical research. Short tandem repeat (STR) and single-nucleotide polymorphism assays are widely used to authenticate biosamples and detect contamination, but with insufficient sensitivity at 5–10% and 3–5%, res...

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Detalles Bibliográficos
Autores principales: Chen, Xiaobo, Qian, Wubin, Song, Zhenzhen, Li, Qi-Xiang, Guo, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Methods Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671372/
https://www.ncbi.nlm.nih.gov/pubmed/33575611
http://dx.doi.org/10.1093/nargab/lqaa060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671372/
https://www.ncbi.nlm.nih.gov/pubmed/33575611
http://dx.doi.org/10.1093/nargab/lqaa060

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