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Authentication, characterization and contamination detection of cell lines, xenografts and organoids by barcode deep NGS sequencing
Misidentification and contamination of biobank samples (e.g. cell lines) have plagued biomedical research. Short tandem repeat (STR) and single-nucleotide polymorphism assays are widely used to authenticate biosamples and detect contamination, but with insufficient sensitivity at 5–10% and 3–5%, res...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671372/ https://www.ncbi.nlm.nih.gov/pubmed/33575611 http://dx.doi.org/10.1093/nargab/lqaa060 |