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Covering all your bases: incorporating intron signal from RNA-seq data

RNA-seq datasets can contain millions of intron reads per library that are typically removed from downstream analysis. Only reads overlapping annotated exons are considered to be informative since mature mRNA is assumed to be the major component sequenced, especially for poly(A) RNA libraries. In th...

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Detalles Bibliográficos
Autores principales:	Lee, Stuart, Zhang, Albert Y, Su, Shian, Ng, Ashley P, Holik, Aliaksei Z, Asselin-Labat, Marie-Liesse, Ritchie, Matthew E, Law, Charity W
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Standard Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671406/ https://www.ncbi.nlm.nih.gov/pubmed/33575621 http://dx.doi.org/10.1093/nargab/lqaa073

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