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Mathematical modeling of hepatitis C RNA replication, exosome secretion and virus release
Hepatitis C virus (HCV) causes acute hepatitis C and can lead to life-threatening complications if it becomes chronic. The HCV genome is a single plus strand of RNA. Its intracellular replication is a spatiotemporally coordinated process of RNA translation upon cell infection, RNA synthesis within a...
Autores principales: | Zitzmann, Carolin, Kaderali, Lars, Perelson, Alan S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671504/ https://www.ncbi.nlm.nih.gov/pubmed/33151933 http://dx.doi.org/10.1371/journal.pcbi.1008421 |
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