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InhA inhibitors have activity against non-replicating Mycobacterium tuberculosis
We previously identified a diazaborine series with potential for development as a new tuberculosis drug. This series has activity in vitro and in vivo and targets cell wall biosynthesis via inhibition of InhA. The overall aim of this study was to determine whether InhA inhibitors have activity again...
Autores principales: | Flint, Lindsay, Korkegian, Aaron, Parish, Tanya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671525/ https://www.ncbi.nlm.nih.gov/pubmed/33201882 http://dx.doi.org/10.1371/journal.pone.0239354 |
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