Cargando…

Differences in the efficiency of 3-deazathiamine and oxythiamine pyrophosphates as inhibitors of pyruvate dehydrogenase complex and growth of HeLa cells in vitro

Oxythiamine (OT) and 3-deazathiamine (DAT) are the antimetabolites of thiamine. The aim of study was to compare the effects of OT and DAT pyrophosphates (-PP) on the kinetics of mammalian pyruvate dehydrogenase complex (PDHC) and the in vitro culture of HeLa cells. The kinetic study showed that 3-de...

Descripción completa

Detalles Bibliográficos
Autores principales:	Grabowska, Ewa, Czerniecka, Magdalena, Czyżewska, Urszula, Zambrzycka, Aneta, Łotowski, Zenon, Tylicki, Adam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671598/ https://www.ncbi.nlm.nih.gov/pubmed/33187452 http://dx.doi.org/10.1080/14756366.2020.1844681

Ejemplares similares

New Steroidal Selenides as Proapoptotic Factors
por: Jastrzebska, Izabella, et al.
Publicado: (2023)

Thiamine and selected thiamine antivitamins — biological activity and methods of synthesis
por: Tylicki, Adam, et al.
Publicado: (2018)

The mechanism of oxythiamine-induced collagen biosynthesis in cultured fibroblasts
por: Szoka, Lukasz, et al.
Publicado: (2015)

Tolerance of Human Fibroblasts to Benfo-Oxythiamine In Vitro
por: Yan, Ming, et al.
Publicado: (2022)

Inhibition of transketolase by oxythiamine altered dynamics of protein signals in pancreatic cancer cells
por: Wang, Jiarui, et al.
Publicado: (2013)

Electrolyte Metabolism in HeLa Cells
por: Wickson-ginzburg, Margaret, et al.
Publicado: (1963)

Editorial: HeLa Cell Sequela
Publicado: (2013)

The fractured genome of HeLa cells
por: Mittelman, David, et al.
Publicado: (2013)

Echinocandins – structure, mechanism of action and use in antifungal therapy
por: Szymański, Mateusz, et al.
Publicado: (2022)

Microtubule-associated proteins of HeLa cells: heat stability of the 200,000 mol wt HeLa MAPs and detection of the presence of MAP-2 in HeLa cell extracts and cycled microtubules
Publicado: (1982)

On the dynamics of the microfilament system in HeLa cells
por: Blikstad, I, et al.
Publicado: (1982)

Exploring the HeLa Dark Mitochondrial Proteome
por: Marini, Federica, et al.
Publicado: (2020)

A dose- and time-dependent effect of oxythiamine on cell growth inhibition in non-small cell lung cancer
por: Bai, Lin, et al.
Publicado: (2021)

Dietary Flavonoids Sensitize HeLa Cells to Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL)
por: Szliszka, Ewelina, et al.
Publicado: (2008)

Role of the Pyruvate Dehydrogenase Complex in Metabolic Remodeling: Differential Pyruvate Dehydrogenase Complex Functions in Metabolism
por: Park, Sungmi, et al.
Publicado: (2018)

Bis[3α,7α,12α-tris(4-nitrobenzoyloxy)-5β-cholan-24-yl] disulfide–ethyl acetate–n-hexane (4/4/1)
por: Brzezinski, Krzysztof, et al.
Publicado: (2010)

Role of pyruvate dehydrogenase complex in traumatic brain injury and Measurement of pyruvate dehydrogenase enzyme by dipstick test
por: Sharma, Pushpa, et al.
Publicado: (2009)

Poly A- Transcripts Expressed in HeLa Cells
por: Wu, Qingfa, et al.
Publicado: (2008)

Hyperthermia and the heat-shock proteins of HeLa cells.
por: Burdon, R. H., et al.
Publicado: (1982)

In vitro polymerization of microtubules from HeLa cells
Publicado: (1978)

Transport and topology of galactosyltransferase in endomembranes of HeLa cells
Publicado: (1983)

Evidence for the autophagy of microinjected proteins in HeLA cells
Publicado: (1977)

Autophagy Facilitates Salmonella Replication in HeLa Cells
por: Yu, Hong B., et al.
Publicado: (2014)

HeLa Sequencing and Genomic Privacy: The Next Chapter
por: Andrews, Brenda J., et al.
Publicado: (2013)

Dynamic influence of Rhein lysinate on HeLa cells
por: Liu, Jiang, et al.
Publicado: (2018)

Cellular Effects of Cyclodextrins: Studies on HeLa Cells
por: Rusznyák, Ágnes, et al.
Publicado: (2022)

Evaluation of Ectopic Mitochondrial DNA in HeLa Cells
por: Hussan, Mohammad T., et al.
Publicado: (2022)

Effects of arsenic on pyruvate dehydrogenase activation.
por: Schiller, C M, et al.
Publicado: (1977)

Transcriptional Regulation of Pyruvate Dehydrogenase Kinase
por: Jeong, Ji Yun, et al.
Publicado: (2012)

Pyruvate dehydrogenase levels are low in sepsis
por: Nuzzo, E, et al.
Publicado: (2015)

Lipophilic Grape Seed Proanthocyanidin Exerts Anti-Cervical Cancer Effects in HeLa Cells and a HeLa-Derived Xenograft Zebrafish Model
por: Li, Changhong, et al.
Publicado: (2022)

Structural and Thermomagnetic Properties of Gallium Nanoferrites and Their Influence on Cells In Vitro
por: Orzechowska, Marta, et al.
Publicado: (2023)

Transporter Molecules influence the Gene Expression in HeLa Cells
por: Waldeck, Waldemar, et al.
Publicado: (2008)

New type of recovery in HeLa cells exposed to bleomycin.
por: Miyamoto, T., et al.
Publicado: (1984)

Hyperthermia enhances the reactivation of irradiated adenovirus in HeLa cells.
por: Piperakis, S. M., et al.
Publicado: (1984)

Intermediary Metabolism in HeLa and Human Foetal Liver Cells
por: Bryant, C., et al.
Publicado: (1963)

Further characterization of HeLa S3 plasma membrane ghosts
Publicado: (1978)

Evidence for RNA linked to nascent DNA in HeLa cells
Publicado: (1976)

A mitotic form of the Golgi apparatus in HeLa cells
Publicado: (1987)

Single-walled carbon nanotube interactions with HeLa cells
por: Yehia, Hadi N, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_i1qj7rrf7pa6077rs90pgrtg0k