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Embryonic origin and serial homology of gill arches and paired fins in the skate, Leucoraja erinacea

Paired fins are a defining feature of the jawed vertebrate body plan, but their evolutionary origin remains unresolved. Gegenbaur proposed that paired fins evolved as gill arch serial homologues, but this hypothesis is now widely discounted, owing largely to the presumed distinct embryonic origins o...

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Autores principales: Sleight, Victoria A, Gillis, J Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671686/
https://www.ncbi.nlm.nih.gov/pubmed/33198887
http://dx.doi.org/10.7554/eLife.60635
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author Sleight, Victoria A
Gillis, J Andrew
author_facet Sleight, Victoria A
Gillis, J Andrew
author_sort Sleight, Victoria A
collection PubMed
description Paired fins are a defining feature of the jawed vertebrate body plan, but their evolutionary origin remains unresolved. Gegenbaur proposed that paired fins evolved as gill arch serial homologues, but this hypothesis is now widely discounted, owing largely to the presumed distinct embryonic origins of these structures from mesoderm and neural crest, respectively. Here, we use cell lineage tracing to test the embryonic origin of the pharyngeal and paired fin skeleton in the skate (Leucoraja erinacea). We find that while the jaw and hyoid arch skeleton derive from neural crest, and the pectoral fin skeleton from mesoderm, the gill arches are of dual origin, receiving contributions from both germ layers. We propose that gill arches and paired fins are serially homologous as derivatives of a continuous, dual-origin mesenchyme with common skeletogenic competence, and that this serial homology accounts for their parallel anatomical organization and shared responses to axial patterning signals.
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spelling pubmed-76716862020-11-18 Embryonic origin and serial homology of gill arches and paired fins in the skate, Leucoraja erinacea Sleight, Victoria A Gillis, J Andrew eLife Developmental Biology Paired fins are a defining feature of the jawed vertebrate body plan, but their evolutionary origin remains unresolved. Gegenbaur proposed that paired fins evolved as gill arch serial homologues, but this hypothesis is now widely discounted, owing largely to the presumed distinct embryonic origins of these structures from mesoderm and neural crest, respectively. Here, we use cell lineage tracing to test the embryonic origin of the pharyngeal and paired fin skeleton in the skate (Leucoraja erinacea). We find that while the jaw and hyoid arch skeleton derive from neural crest, and the pectoral fin skeleton from mesoderm, the gill arches are of dual origin, receiving contributions from both germ layers. We propose that gill arches and paired fins are serially homologous as derivatives of a continuous, dual-origin mesenchyme with common skeletogenic competence, and that this serial homology accounts for their parallel anatomical organization and shared responses to axial patterning signals. eLife Sciences Publications, Ltd 2020-11-17 /pmc/articles/PMC7671686/ /pubmed/33198887 http://dx.doi.org/10.7554/eLife.60635 Text en © 2020, Sleight and Gillis http://creativecommons.org/licenses/by/4.0/ http://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Developmental Biology
Sleight, Victoria A
Gillis, J Andrew
Embryonic origin and serial homology of gill arches and paired fins in the skate, Leucoraja erinacea
title Embryonic origin and serial homology of gill arches and paired fins in the skate, Leucoraja erinacea
title_full Embryonic origin and serial homology of gill arches and paired fins in the skate, Leucoraja erinacea
title_fullStr Embryonic origin and serial homology of gill arches and paired fins in the skate, Leucoraja erinacea
title_full_unstemmed Embryonic origin and serial homology of gill arches and paired fins in the skate, Leucoraja erinacea
title_short Embryonic origin and serial homology of gill arches and paired fins in the skate, Leucoraja erinacea
title_sort embryonic origin and serial homology of gill arches and paired fins in the skate, leucoraja erinacea
topic Developmental Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671686/
https://www.ncbi.nlm.nih.gov/pubmed/33198887
http://dx.doi.org/10.7554/eLife.60635
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