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Embryonic origin and serial homology of gill arches and paired fins in the skate, Leucoraja erinacea
Paired fins are a defining feature of the jawed vertebrate body plan, but their evolutionary origin remains unresolved. Gegenbaur proposed that paired fins evolved as gill arch serial homologues, but this hypothesis is now widely discounted, owing largely to the presumed distinct embryonic origins o...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671686/ https://www.ncbi.nlm.nih.gov/pubmed/33198887 http://dx.doi.org/10.7554/eLife.60635 |
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author | Sleight, Victoria A Gillis, J Andrew |
author_facet | Sleight, Victoria A Gillis, J Andrew |
author_sort | Sleight, Victoria A |
collection | PubMed |
description | Paired fins are a defining feature of the jawed vertebrate body plan, but their evolutionary origin remains unresolved. Gegenbaur proposed that paired fins evolved as gill arch serial homologues, but this hypothesis is now widely discounted, owing largely to the presumed distinct embryonic origins of these structures from mesoderm and neural crest, respectively. Here, we use cell lineage tracing to test the embryonic origin of the pharyngeal and paired fin skeleton in the skate (Leucoraja erinacea). We find that while the jaw and hyoid arch skeleton derive from neural crest, and the pectoral fin skeleton from mesoderm, the gill arches are of dual origin, receiving contributions from both germ layers. We propose that gill arches and paired fins are serially homologous as derivatives of a continuous, dual-origin mesenchyme with common skeletogenic competence, and that this serial homology accounts for their parallel anatomical organization and shared responses to axial patterning signals. |
format | Online Article Text |
id | pubmed-7671686 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | eLife Sciences Publications, Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-76716862020-11-18 Embryonic origin and serial homology of gill arches and paired fins in the skate, Leucoraja erinacea Sleight, Victoria A Gillis, J Andrew eLife Developmental Biology Paired fins are a defining feature of the jawed vertebrate body plan, but their evolutionary origin remains unresolved. Gegenbaur proposed that paired fins evolved as gill arch serial homologues, but this hypothesis is now widely discounted, owing largely to the presumed distinct embryonic origins of these structures from mesoderm and neural crest, respectively. Here, we use cell lineage tracing to test the embryonic origin of the pharyngeal and paired fin skeleton in the skate (Leucoraja erinacea). We find that while the jaw and hyoid arch skeleton derive from neural crest, and the pectoral fin skeleton from mesoderm, the gill arches are of dual origin, receiving contributions from both germ layers. We propose that gill arches and paired fins are serially homologous as derivatives of a continuous, dual-origin mesenchyme with common skeletogenic competence, and that this serial homology accounts for their parallel anatomical organization and shared responses to axial patterning signals. eLife Sciences Publications, Ltd 2020-11-17 /pmc/articles/PMC7671686/ /pubmed/33198887 http://dx.doi.org/10.7554/eLife.60635 Text en © 2020, Sleight and Gillis http://creativecommons.org/licenses/by/4.0/ http://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited. |
spellingShingle | Developmental Biology Sleight, Victoria A Gillis, J Andrew Embryonic origin and serial homology of gill arches and paired fins in the skate, Leucoraja erinacea |
title | Embryonic origin and serial homology of gill arches and paired fins in the skate, Leucoraja erinacea |
title_full | Embryonic origin and serial homology of gill arches and paired fins in the skate, Leucoraja erinacea |
title_fullStr | Embryonic origin and serial homology of gill arches and paired fins in the skate, Leucoraja erinacea |
title_full_unstemmed | Embryonic origin and serial homology of gill arches and paired fins in the skate, Leucoraja erinacea |
title_short | Embryonic origin and serial homology of gill arches and paired fins in the skate, Leucoraja erinacea |
title_sort | embryonic origin and serial homology of gill arches and paired fins in the skate, leucoraja erinacea |
topic | Developmental Biology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671686/ https://www.ncbi.nlm.nih.gov/pubmed/33198887 http://dx.doi.org/10.7554/eLife.60635 |
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