Spatially compartmentalized phase regulation of a Ca(2+)-cAMP-PKA oscillatory circuit

Signaling networks are spatiotemporally organized to sense diverse inputs, process information, and carry out specific cellular tasks. In β cells, Ca(2+), cyclic adenosine monophosphate (cAMP), and Protein Kinase A (PKA) exist in an oscillatory circuit characterized by a high degree of feedback. Her...

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Detalles Bibliográficos
Autores principales: Tenner, Brian, Getz, Michael, Ross, Brian, Ohadi, Donya, Bohrer, Christopher H, Greenwald, Eric, Mehta, Sohum, Xiao, Jie, Rangamani, Padmini, Zhang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671691/
https://www.ncbi.nlm.nih.gov/pubmed/33201801
http://dx.doi.org/10.7554/eLife.55013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671691/
https://www.ncbi.nlm.nih.gov/pubmed/33201801
http://dx.doi.org/10.7554/eLife.55013

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