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Spatially compartmentalized phase regulation of a Ca(2+)-cAMP-PKA oscillatory circuit
Signaling networks are spatiotemporally organized to sense diverse inputs, process information, and carry out specific cellular tasks. In β cells, Ca(2+), cyclic adenosine monophosphate (cAMP), and Protein Kinase A (PKA) exist in an oscillatory circuit characterized by a high degree of feedback. Her...
Autores principales: | Tenner, Brian, Getz, Michael, Ross, Brian, Ohadi, Donya, Bohrer, Christopher H, Greenwald, Eric, Mehta, Sohum, Xiao, Jie, Rangamani, Padmini, Zhang, Jin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671691/ https://www.ncbi.nlm.nih.gov/pubmed/33201801 http://dx.doi.org/10.7554/eLife.55013 |
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