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Engeletin ameliorates pulmonary fibrosis through endoplasmic reticulum stress depending on lnc949-mediated TGF-β1-Smad2/3 and JNK signalling pathways
CONTEXT: Pulmonary fibrosis (PF) is a highly heterogeneous and lethal pathological process having no effective drug. Engeletin exerts multiple biological activities including anti-inflammatory and lung repair. Whether engeletin has therapeutic effects on PF remains unclear. OBJECTIVE: Examining effe...
Autores principales: | Zhang, Jinjin, Chen, Xiaoqing, Chen, Hongbin, Li, Rongrong, Xu, Pan, Lv, Changjun, Liu, Bo, Song, Xiaodong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671710/ https://www.ncbi.nlm.nih.gov/pubmed/33181025 http://dx.doi.org/10.1080/13880209.2020.1834590 |
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